This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1en7

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (05:58, 3 April 2024) (edit) (undo)
 
(12 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1en7.png|left|200px]]
 
-
<!--
+
==ENDONUCLEASE VII (ENDOVII) FROM PHAGE T4==
-
The line below this paragraph, containing "STRUCTURE_1en7", creates the "Structure Box" on the page.
+
<StructureSection load='1en7' size='340' side='right'caption='[[1en7]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1en7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EN7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EN7 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
{{STRUCTURE_1en7| PDB=1en7 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1en7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1en7 OCA], [https://pdbe.org/1en7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1en7 RCSB], [https://www.ebi.ac.uk/pdbsum/1en7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1en7 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/END7_BPT4 END7_BPT4] Cleaves DNA cruciform and Y-structures as well as heteroduplex loops. Resolves Holliday junctions, recognizes a broad spectrum of DNA substrates ranging from branched DNAs to single base mismatches.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/en/1en7_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1en7 ConSurf].
 +
<div style="clear:both"></div>
-
===ENDONUCLEASE VII (ENDOVII) FROM PHAGE T4===
+
==See Also==
-
 
+
*[[Endonuclease 3D structures|Endonuclease 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_10075917}}, adds the Publication Abstract to the page
+
[[Category: Escherichia virus T4]]
-
(as it appears on PubMed at http://www.pubmed.gov), where 10075917 is the PubMed ID number.
+
[[Category: Large Structures]]
-
-->
+
[[Category: Raaijmakers H]]
-
{{ABSTRACT_PUBMED_10075917}}
+
[[Category: Suck D]]
-
 
+
[[Category: Toro I]]
-
==About this Structure==
+
[[Category: Vix O]]
-
1EN7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EN7 OCA].
+
-
 
+
-
==Reference==
+
-
X-ray structure of T4 endonuclease VII: a DNA junction resolvase with a novel fold and unusual domain-swapped dimer architecture., Raaijmakers H, Vix O, Toro I, Golz S, Kemper B, Suck D, EMBO J. 1999 Mar 15;18(6):1447-58. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10075917 10075917]
+
-
[[Category: Crossover junction endodeoxyribonuclease]]
+
-
[[Category: Enterobacteria phage t4]]
+
-
[[Category: Single protein]]
+
-
[[Category: Raaijmakers, H.]]
+
-
[[Category: Suck, D.]]
+
-
[[Category: Toro, I.]]
+
-
[[Category: Vix, O.]]
+
-
[[Category: Dnase]]
+
-
[[Category: Endonuclease]]
+
-
[[Category: Holliday junction]]
+
-
[[Category: Resolvase]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 01:02:34 2008''
+

Current revision

ENDONUCLEASE VII (ENDOVII) FROM PHAGE T4

PDB ID 1en7

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1en7"
Personal tools