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1ixp

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{{Seed}}
 
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[[Image:1ixp.png|left|200px]]
 
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<!--
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==Enzyme-phosphate Complex of Pyridoxine 5'-Phosphate synthase==
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The line below this paragraph, containing "STRUCTURE_1ixp", creates the "Structure Box" on the page.
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<StructureSection load='1ixp' size='340' side='right'caption='[[1ixp]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1ixp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IXP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IXP FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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{{STRUCTURE_1ixp| PDB=1ixp | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ixp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ixp OCA], [https://pdbe.org/1ixp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ixp RCSB], [https://www.ebi.ac.uk/pdbsum/1ixp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ixp ProSAT]</span></td></tr>
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</table>
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===Enzyme-phosphate Complex of Pyridoxine 5'-Phosphate synthase===
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== Function ==
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[https://www.uniprot.org/uniprot/PDXJ_ECOLI PDXJ_ECOLI] Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.<ref>PMID:10225425</ref>
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== Evolutionary Conservation ==
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<!--
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_12206776}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 12206776 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ix/1ixp_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_12206776}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1IXP is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IXP OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ixp ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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<ref group="xtra">PMID:12206776</ref><references group="xtra"/>
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<references/>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Clausen, T.]]
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[[Category: Large Structures]]
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[[Category: Garrido-Franco, M.]]
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[[Category: Clausen T]]
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[[Category: Huber, R.]]
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[[Category: Garrido-Franco M]]
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[[Category: Laber, B.]]
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[[Category: Huber R]]
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[[Category: Enzyme-ligand complex]]
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[[Category: Laber B]]
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[[Category: Open-closed transition]]
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[[Category: Tim barrel]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:24:48 2009''
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Current revision

Enzyme-phosphate Complex of Pyridoxine 5'-Phosphate synthase

PDB ID 1ixp

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