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1j4a

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[[Image:1j4a.png|left|200px]]
 
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{{STRUCTURE_1j4a| PDB=1j4a | SCENE= }}
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==INSIGHTS INTO DOMAIN CLOSURE, SUBSTRATE SPECIFICITY AND CATALYSIS OF D-LACTATE DEHYDROGENASE FROM LACTOBACILLUS BULGARICUS==
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<StructureSection load='1j4a' size='340' side='right'caption='[[1j4a]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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===INSIGHTS INTO DOMAIN CLOSURE, SUBSTRATE SPECIFICITY AND CATALYSIS OF D-LACTATE DEHYDROGENASE FROM LACTOBACILLUS BULGARICUS===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1j4a]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Lactobacillus_delbrueckii_subsp._bulgaricus Lactobacillus delbrueckii subsp. bulgaricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J4A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J4A FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12054772}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j4a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j4a OCA], [https://pdbe.org/1j4a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j4a RCSB], [https://www.ebi.ac.uk/pdbsum/1j4a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j4a ProSAT]</span></td></tr>
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[[1j4a]] is a 4 chain structure of [[Lactate Dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Lactobacillus_delbrueckii_subsp._bulgaricus Lactobacillus delbrueckii subsp. bulgaricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J4A OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LDHD_LACDA LDHD_LACDA]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j4/1j4a_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1j4a ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Lactate Dehydrogenase|Lactate Dehydrogenase]]
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*[[Lactate dehydrogenase 3D structures|Lactate dehydrogenase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:012054772</ref><references group="xtra"/>
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[[Category: D-lactate dehydrogenase]]
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[[Category: Lactobacillus delbrueckii subsp. bulgaricus]]
[[Category: Lactobacillus delbrueckii subsp. bulgaricus]]
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[[Category: Dauter, M.]]
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[[Category: Large Structures]]
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[[Category: Hottinger, H.]]
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[[Category: Dauter M]]
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[[Category: Kochhar, S.]]
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[[Category: Hottinger H]]
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[[Category: Lamzin, V S.]]
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[[Category: Kochhar S]]
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[[Category: Razeto, A.]]
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[[Category: Lamzin VS]]
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[[Category: Wilson, K S.]]
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[[Category: Razeto A]]
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[[Category: Nad-dependent dehydrogenase]]
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[[Category: Wilson KS]]
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[[Category: Oxidoreductase]]
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[[Category: Reversible interconversion of pyruvate into d-lactate]]
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Current revision

INSIGHTS INTO DOMAIN CLOSURE, SUBSTRATE SPECIFICITY AND CATALYSIS OF D-LACTATE DEHYDROGENASE FROM LACTOBACILLUS BULGARICUS

PDB ID 1j4a

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