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1mk8

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[[Image:1mk8.png|left|200px]]
 
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{{STRUCTURE_1mk8| PDB=1mk8 | SCENE= }}
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==Crystal Structure of a Mutant Cytochrome c Peroxidase showing a Novel Trp-Tyr Covalent Cross-link==
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<StructureSection load='1mk8' size='340' side='right'caption='[[1mk8]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
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===Crystal Structure of a Mutant Cytochrome c Peroxidase showing a Novel Trp-Tyr Covalent Cross-link===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1mk8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MK8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MK8 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12684005}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mk8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mk8 OCA], [https://pdbe.org/1mk8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mk8 RCSB], [https://www.ebi.ac.uk/pdbsum/1mk8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mk8 ProSAT]</span></td></tr>
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[[1mk8]] is a 1 chain structure of [[Cytochrome c peroxidase]] with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MK8 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CCPR_YEAST CCPR_YEAST] Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mk/1mk8_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mk8 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Cytochrome c peroxidase|Cytochrome c peroxidase]]
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*[[Cytochrome c peroxidase 3D structures|Cytochrome c peroxidase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:012684005</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Cytochrome-c peroxidase]]
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[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Bhaskar, B.]]
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[[Category: Bhaskar B]]
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[[Category: Farmer, P J.]]
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[[Category: Farmer PJ]]
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[[Category: Immoos, C E.]]
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[[Category: Immoos CE]]
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[[Category: Poulos, T L.]]
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[[Category: Poulos TL]]
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[[Category: Shimizu, H.]]
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[[Category: Shimizu H]]
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[[Category: Cytochrome c peroxidase]]
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[[Category: Oxidoreductase]]
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[[Category: Oxygen radical]]
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[[Category: Trp cation radical]]
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[[Category: Tryptophan-tyrosine cross-link]]
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Current revision

Crystal Structure of a Mutant Cytochrome c Peroxidase showing a Novel Trp-Tyr Covalent Cross-link

PDB ID 1mk8

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