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1n04

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{{Seed}}
 
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[[Image:1n04.png|left|200px]]
 
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==Diferric chicken serum transferrin at 2.8 A resolution.==
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The line below this paragraph, containing "STRUCTURE_1n04", creates the "Structure Box" on the page.
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<StructureSection load='1n04' size='340' side='right'caption='[[1n04]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1n04]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N04 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N04 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FUL:BETA-L-FUCOSE'>FUL</scene></td></tr>
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{{STRUCTURE_1n04| PDB=1n04 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n04 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n04 OCA], [https://pdbe.org/1n04 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n04 RCSB], [https://www.ebi.ac.uk/pdbsum/1n04 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n04 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TRFE_CHICK TRFE_CHICK] Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. There are two forms of hen transferrin, ovotransferrin, found in the ovoducts and, serum transferrin, secreted by the liver. Serum transferrin may also have a role in stimulating cell proliferation and is regulated by iron levels. Ovotransferrin has a bacteriostatic function and, is not controlled by iron levels.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n0/1n04_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1n04 ConSurf].
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<div style="clear:both"></div>
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===Diferric chicken serum transferrin at 2.8 A resolution.===
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==See Also==
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*[[Transferrin 3D structures|Transferrin 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_14501117}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 14501117 is the PubMed ID number.
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{{ABSTRACT_PUBMED_14501117}}
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==About this Structure==
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1N04 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N04 OCA].
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==Reference==
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Structure of diferric hen serum transferrin at 2.8 A resolution., Guha Thakurta P, Choudhury D, Dasgupta R, Dattagupta JK, Acta Crystallogr D Biol Crystallogr. 2003 Oct;59(Pt 10):1773-81. Epub 2003, Sep 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14501117 14501117]
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[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Choudhury, D.]]
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[[Category: Choudhury D]]
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[[Category: Dasgupta, R.]]
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[[Category: Dasgupta R]]
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[[Category: Dattagupta, J K.]]
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[[Category: Dattagupta JK]]
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[[Category: Thakurta, P Guha.]]
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[[Category: Guha Thakurta P]]
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[[Category: Bilobal]]
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[[Category: Iron transport]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 01:38:46 2008''
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Current revision

Diferric chicken serum transferrin at 2.8 A resolution.

PDB ID 1n04

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