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1pz0

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{{Seed}}
 
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[[Image:1pz0.png|left|200px]]
 
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==Structure of NADPH-dependent family 11 aldo-keto reductase AKR11A(holo)==
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The line below this paragraph, containing "STRUCTURE_1pz0", creates the "Structure Box" on the page.
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<StructureSection load='1pz0' size='340' side='right'caption='[[1pz0]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1pz0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PZ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PZ0 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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{{STRUCTURE_1pz0| PDB=1pz0 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pz0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pz0 OCA], [https://pdbe.org/1pz0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pz0 RCSB], [https://www.ebi.ac.uk/pdbsum/1pz0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pz0 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/IOLS_BACSU IOLS_BACSU]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pz/1pz0_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pz0 ConSurf].
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<div style="clear:both"></div>
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===Structure of NADPH-dependent family 11 aldo-keto reductase AKR11A(holo)===
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==See Also==
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*[[Aldo-keto reductase 3D structures|Aldo-keto reductase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_15019785}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 15019785 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15019785}}
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==About this Structure==
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1PZ0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PZ0 OCA].
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==Reference==
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Structural and catalytic diversity in the two family 11 aldo-keto reductases., Ehrensberger AH, Wilson DK, J Mol Biol. 2004 Mar 26;337(3):661-73. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15019785 15019785]
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[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Ehrensberger, A H.]]
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[[Category: Ehrensberger AH]]
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[[Category: Wilson, D K.]]
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[[Category: Wilson DK]]
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[[Category: Aldo-keto reductase]]
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[[Category: Beta-alpha barrel]]
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[[Category: Tim barrel]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 06:00:37 2008''
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Current revision

Structure of NADPH-dependent family 11 aldo-keto reductase AKR11A(holo)

PDB ID 1pz0

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