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1z9d

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==Crystal structure of a putative uridylate kinase (UMP-kinase) from Streptococcus pyogenes==
==Crystal structure of a putative uridylate kinase (UMP-kinase) from Streptococcus pyogenes==
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<StructureSection load='1z9d' size='340' side='right' caption='[[1z9d]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='1z9d' size='340' side='right'caption='[[1z9d]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1z9d]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pyogenes Streptococcus pyogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z9D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z9D FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1z9d]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pyogenes Streptococcus pyogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z9D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z9D FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pyrH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1314 Streptococcus pyogenes])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z9d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z9d OCA], [https://pdbe.org/1z9d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z9d RCSB], [https://www.ebi.ac.uk/pdbsum/1z9d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z9d ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1z9d TOPSAN]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z9d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z9d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z9d RCSB], [http://www.ebi.ac.uk/pdbsum/1z9d PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/1z9d TOPSAN]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/PYRH_STRP1 PYRH_STRP1] Catalyzes the reversible phosphorylation of UMP to UDP (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z9/1z9d_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z9/1z9d_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1z9d ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Streptococcus pyogenes]]
[[Category: Streptococcus pyogenes]]
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[[Category: Burley, S K.]]
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[[Category: Burley SK]]
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[[Category: Kniewel, R.]]
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[[Category: Kniewel R]]
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[[Category: Lee, K.]]
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[[Category: Lee K]]
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[[Category: Lima, C D.]]
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[[Category: Lima CD]]
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[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics.]]
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[[Category: Rajashankar KR]]
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[[Category: Rajashankar, K R.]]
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[[Category: New york sgx research center for structural genomic]]
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[[Category: Nysgxrc]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Putative uridylate kinase]]
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[[Category: Pyrh]]
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[[Category: Structural genomic]]
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[[Category: T1668]]
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[[Category: Transferase]]
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[[Category: Ump-kinase]]
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Current revision

Crystal structure of a putative uridylate kinase (UMP-kinase) from Streptococcus pyogenes

PDB ID 1z9d

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