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2a9n

From Proteopedia

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{{Seed}}
 
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[[Image:2a9n.png|left|200px]]
 
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==A Mutation Designed to Alter Crystal Packing Permits Structural Analysis of a Tight-binding Fluorescein-scFv complex==
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The line below this paragraph, containing "STRUCTURE_2a9n", creates the "Structure Box" on the page.
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<StructureSection load='2a9n' size='340' side='right'caption='[[2a9n]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2a9n]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A9N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A9N FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ORE:4-(2,7-DIFLUORO-6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)ISOPHTHALIC+ACID'>ORE</scene></td></tr>
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{{STRUCTURE_2a9n| PDB=2a9n | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a9n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a9n OCA], [https://pdbe.org/2a9n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a9n RCSB], [https://www.ebi.ac.uk/pdbsum/2a9n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a9n ProSAT]</span></td></tr>
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</table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a9/2a9n_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2a9n ConSurf].
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<div style="clear:both"></div>
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===A Mutation Designed to Alter Crystal Packing Permits Structural Analysis of a Tight-binding Fluorescein-scFv complex===
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==See Also==
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*[[Antibody 3D structures|Antibody 3D structures]]
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*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
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<!--
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*[[3D structures of human antibody|3D structures of human antibody]]
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The line below this paragraph, {{ABSTRACT_PUBMED_16195545}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 16195545 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_16195545}}
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==About this Structure==
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2A9N is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A9N OCA].
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==Reference==
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A mutation designed to alter crystal packing permits structural analysis of a tight-binding fluorescein-scFv complex., Honegger A, Spinelli S, Cambillau C, Pluckthun A, Protein Sci. 2005 Oct;14(10):2537-49. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16195545 16195545]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Cambillau, C.]]
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[[Category: Cambillau C]]
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[[Category: Honegger, A.]]
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[[Category: Honegger A]]
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[[Category: Pluckthun, A.]]
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[[Category: Pluckthun A]]
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[[Category: Spinelli, S.]]
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[[Category: Spinelli S]]
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[[Category: Fluorescein]]
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[[Category: Immunoglobulin]]
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[[Category: Scfv]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 11:36:54 2008''
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Current revision

A Mutation Designed to Alter Crystal Packing Permits Structural Analysis of a Tight-binding Fluorescein-scFv complex

PDB ID 2a9n

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