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2f6l
From Proteopedia
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| - | [[Image:2f6l.png|left|200px]] | ||
| - | + | ==X-ray structure of Chorismate Mutase from Mycobacterium Tuberculosis== | |
| + | <StructureSection load='2f6l' size='340' side='right'caption='[[2f6l]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2f6l]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F6L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F6L FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f6l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f6l OCA], [https://pdbe.org/2f6l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f6l RCSB], [https://www.ebi.ac.uk/pdbsum/2f6l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f6l ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SCMU_MYCTU SCMU_MYCTU] Catalyzes the Claisen rearrangement of chorismate to prephenate. May play some role in the pathogenicity.<ref>PMID:15654876</ref> <ref>PMID:15737998</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f6/2f6l_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f6l ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[3D structures of chorismate mutase|3D structures of chorismate mutase]] | |
| - | + | == References == | |
| - | + | <references/> | |
| - | + | __TOC__ | |
| - | [[ | + | </StructureSection> |
| - | + | [[Category: Large Structures]] | |
| - | == | + | [[Category: Mycobacterium tuberculosis H37Rv]] |
| - | < | + | [[Category: Gilliland GL]] |
| - | [[Category: | + | [[Category: Howard AJ]] |
| - | [[Category: Mycobacterium tuberculosis]] | + | [[Category: Kim SK]] |
| - | [[Category: Gilliland | + | [[Category: Ladner JE]] |
| - | [[Category: Howard | + | [[Category: Reddy PT]] |
| - | [[Category: Kim | + | |
| - | [[Category: Ladner | + | |
| - | [[Category: Reddy | + | |
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
X-ray structure of Chorismate Mutase from Mycobacterium Tuberculosis
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