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2f6l

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{{Seed}}
 
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[[Image:2f6l.png|left|200px]]
 
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==X-ray structure of Chorismate Mutase from Mycobacterium Tuberculosis==
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The line below this paragraph, containing "STRUCTURE_2f6l", creates the "Structure Box" on the page.
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<StructureSection load='2f6l' size='340' side='right'caption='[[2f6l]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2f6l]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F6L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F6L FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f6l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f6l OCA], [https://pdbe.org/2f6l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f6l RCSB], [https://www.ebi.ac.uk/pdbsum/2f6l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f6l ProSAT]</span></td></tr>
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{{STRUCTURE_2f6l| PDB=2f6l | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SCMU_MYCTU SCMU_MYCTU] Catalyzes the Claisen rearrangement of chorismate to prephenate. May play some role in the pathogenicity.<ref>PMID:15654876</ref> <ref>PMID:15737998</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f6/2f6l_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f6l ConSurf].
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<div style="clear:both"></div>
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===X-ray structure of Chorismate Mutase from Mycobacterium Tuberculosis===
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==See Also==
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*[[3D structures of chorismate mutase|3D structures of chorismate mutase]]
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_17146044}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 17146044 is the PubMed ID number.
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</StructureSection>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_17146044}}
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Gilliland GL]]
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==About this Structure==
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[[Category: Howard AJ]]
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2F6L is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F6L OCA].
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[[Category: Kim SK]]
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[[Category: Ladner JE]]
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==Reference==
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[[Category: Reddy PT]]
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Biochemical and structural characterization of the secreted chorismate mutase (Rv1885c) from Mycobacterium tuberculosis H37Rv: an *AroQ enzyme not regulated by the aromatic amino acids., Kim SK, Reddy SK, Nelson BC, Vasquez GB, Davis A, Howard AJ, Patterson S, Gilliland GL, Ladner JE, Reddy PT, J Bacteriol. 2006 Dec;188(24):8638-48. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17146044 17146044]
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[[Category: Chorismate mutase]]
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[[Category: Mycobacterium tuberculosis h37rv]]
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[[Category: Single protein]]
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[[Category: Gilliland, G L.]]
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[[Category: Howard, A J.]]
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[[Category: Kim, S K.]]
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[[Category: Ladner, J E.]]
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[[Category: Reddy, P T.]]
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[[Category: Dimer]]
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[[Category: Helical]]
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[[Category: Isomerase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 17 13:07:36 2008''
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Current revision

X-ray structure of Chorismate Mutase from Mycobacterium Tuberculosis

PDB ID 2f6l

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