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2pb0

From Proteopedia

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[[Image:2pb0.png|left|200px]]
 
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{{STRUCTURE_2pb0| PDB=2pb0 | SCENE= }}
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==Structure of biosynthetic N-acetylornithine aminotransferase from Salmonella typhimurium: studies on substrate specificity and inhibitor binding==
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<StructureSection load='2pb0' size='340' side='right'caption='[[2pb0]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
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===Structure of biosynthetic N-acetylornithine aminotransferase from Salmonella typhimurium: studies on substrate specificity and inhibitor binding===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2pb0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PB0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PB0 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_17680699}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.96&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pb0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pb0 OCA], [https://pdbe.org/2pb0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pb0 RCSB], [https://www.ebi.ac.uk/pdbsum/2pb0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pb0 ProSAT]</span></td></tr>
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[[2pb0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PB0 OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/ARGD_SALTY ARGD_SALTY] Involved in both the arginine and lysine biosynthetic pathways (By similarity).[HAMAP-Rule:MF_01107]
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<ref group="xtra">PMID:017680699</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Murthy, M R.N.]]
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Check<jmol>
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[[Category: Prasuna, P Ratna.]]
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<jmolCheckbox>
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[[Category: Rajaram, V.]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pb/2pb0_consurf.spt"</scriptWhenChecked>
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[[Category: Savithri, H S.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Argd]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Arginine metabolism]]
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</jmolCheckbox>
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[[Category: Gabaculine]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pb0 ConSurf].
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[[Category: Lysine biosynthesis]]
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<div style="clear:both"></div>
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[[Category: Pyridoxal-5'-phosphate]]
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__TOC__
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[[Category: Transferase]]
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
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[[Category: Murthy MRN]]
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[[Category: Rajaram V]]
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[[Category: Ratna Prasuna P]]
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[[Category: Savithri HS]]

Current revision

Structure of biosynthetic N-acetylornithine aminotransferase from Salmonella typhimurium: studies on substrate specificity and inhibitor binding

PDB ID 2pb0

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