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2phm

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[[Image:2phm.png|left|200px]]
 
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{{STRUCTURE_2phm| PDB=2phm | SCENE= }}
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==STRUCTURE OF PHENYLALANINE HYDROXYLASE DEPHOSPHORYLATED==
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<StructureSection load='2phm' size='340' side='right'caption='[[2phm]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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===STRUCTURE OF PHENYLALANINE HYDROXYLASE DEPHOSPHORYLATED===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2phm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PHM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PHM FirstGlance]. <br>
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{{ABSTRACT_PUBMED_10331871}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2phm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2phm OCA], [https://pdbe.org/2phm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2phm RCSB], [https://www.ebi.ac.uk/pdbsum/2phm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2phm ProSAT]</span></td></tr>
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[[2phm]] is a 1 chain structure of [[Phenylalanine hydroxylase]] with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PHM OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PH4H_RAT PH4H_RAT]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ph/2phm_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2phm ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Phenylalanine hydroxylase|Phenylalanine hydroxylase]]
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*[[Hydroxylases 3D structures|Hydroxylases 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:010331871</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Phenylalanine 4-monooxygenase]]
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[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Cotton, R G.]]
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[[Category: Cotton RG]]
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[[Category: House, C M.]]
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[[Category: House CM]]
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[[Category: Jennings, I G.]]
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[[Category: Jennings IG]]
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[[Category: Kemp, B E.]]
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[[Category: Kemp BE]]
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[[Category: Kobe, B.]]
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[[Category: Kobe B]]
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[[Category: Michell, B J.]]
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[[Category: Michell BJ]]
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[[Category: Allosteric regulation]]
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[[Category: Aromatic amino acid hydroxylase]]
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[[Category: Intrasteric regulation]]
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[[Category: Oxidoreductase]]
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[[Category: Phenylalanine hydroxylase]]
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[[Category: Phosphorylation]]
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Current revision

STRUCTURE OF PHENYLALANINE HYDROXYLASE DEPHOSPHORYLATED

PDB ID 2phm

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