This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2pos

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px {{Structure |PDB= 2pos |SIZE=350|CAPTION= <scene name='initialview01'>2pos</scene>, resolution 1.600&Aring; |SITE= <scene name='pdbsite=AC1:Ni+Binding+Site+...)
Current revision (06:31, 3 April 2024) (edit) (undo)
 
(12 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2pos.jpg|left|200px]]
 
-
{{Structure
+
==Crystal Structure of sylvaticin, a new secreted protein from pythium sylvaticum==
-
|PDB= 2pos |SIZE=350|CAPTION= <scene name='initialview01'>2pos</scene>, resolution 1.600&Aring;
+
<StructureSection load='2pos' size='340' side='right'caption='[[2pos]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
-
|SITE= <scene name='pdbsite=AC1:Ni+Binding+Site+For+Residue+B+100'>AC1</scene>, <scene name='pdbsite=AC2:Ni+Binding+Site+For+Residue+C+100'>AC2</scene>, <scene name='pdbsite=AC3:Ni+Binding+Site+For+Residue+D+100'>AC3</scene>, <scene name='pdbsite=AC4:Ni+Binding+Site+For+Residue+A+100'>AC4</scene>, <scene name='pdbsite=AC5:Cl+Binding+Site+For+Residue+A+3000'>AC5</scene>, <scene name='pdbsite=AC6:Trs+Binding+Site+For+Residue+B+2000'>AC6</scene>, <scene name='pdbsite=AC7:Trs+Binding+Site+For+Residue+C+2001'>AC7</scene>, <scene name='pdbsite=AC8:Trs+Binding+Site+For+Residue+D+2002'>AC8</scene> and <scene name='pdbsite=AC9:Trs+Binding+Site+For+Residue+A+2003'>AC9</scene>
+
== Structural highlights ==
-
|LIGAND= <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene> and <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>
+
<table><tr><td colspan='2'>[[2pos]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Globisporangium_sylvaticum Globisporangium sylvaticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2POS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2POS FirstGlance]. <br>
-
|ACTIVITY=
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
-
|GENE=
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
-
}}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pos FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pos OCA], [https://pdbe.org/2pos PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pos RCSB], [https://www.ebi.ac.uk/pdbsum/2pos PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pos ProSAT]</span></td></tr>
-
 
+
</table>
-
'''Crystal Structure of sylvaticin, a new secreted protein from pythium sylvaticum'''
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/D0VWX7_9STRA D0VWX7_9STRA]
-
 
+
== Evolutionary Conservation ==
-
==Overview==
+
[[Image:Consurf_key_small.gif|200px|right]]
-
The structure of sylvaticin, a 10 kDa major pythin protein excreted by the parasitic oomycete Pythium sylvaticum, has been determined. Although closely related to alpha-elicitins in its biological response, toxicity and overall structure, sylvaticin presents a number of structural features that make it an unusual member of the elicitin class. Elicitins possess a large hydrophobic cavity and the mechanism of the systemic acquired resistance induced in planta is known to proceed through lipid transport and complexation within this cavity. Unlike other elicitins, sylvaticin contains tryptophan residues, one of which points inwards towards the central cavity, thus limiting access to sterols. In the case of sylvaticin, the sterol-transport mechanism is likely to be of less importance compared with other members of the elicitin family and still remains to be fully characterized.
+
Check<jmol>
-
 
+
<jmolCheckbox>
-
==About this Structure==
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/po/2pos_consurf.spt"</scriptWhenChecked>
-
2POS is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Pythium_sylvaticum Pythium sylvaticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2POS OCA].
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
 
+
<text>to colour the structure by Evolutionary Conservation</text>
-
==Reference==
+
</jmolCheckbox>
-
Structure of sylvaticin, a new alpha-elicitin-like protein from Pythium sylvaticum., Lascombe MB, Retailleau P, Ponchet M, Industri B, Blein JP, Prange T, Acta Crystallogr D Biol Crystallogr. 2007 Oct;63(Pt 10):1102-8. Epub 2007, Sep 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17881828 17881828]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pos ConSurf].
-
[[Category: Protein complex]]
+
<div style="clear:both"></div>
-
[[Category: Pythium sylvaticum]]
+
__TOC__
-
[[Category: Lascombe, M B.]]
+
</StructureSection>
-
[[Category: Prange, T.]]
+
[[Category: Globisporangium sylvaticum]]
-
[[Category: CL]]
+
[[Category: Large Structures]]
-
[[Category: NI]]
+
[[Category: Lascombe MB]]
-
[[Category: TRS]]
+
[[Category: Prange T]]
-
[[Category: elicitin]]
+
-
[[Category: sylvaticin]]
+
-
[[Category: toxin]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:15:45 2008''
+

Current revision

Crystal Structure of sylvaticin, a new secreted protein from pythium sylvaticum

PDB ID 2pos

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2pos"
Personal tools