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3ejb

From Proteopedia

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[[Image:3ejb.png|left|200px]]
 
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{{STRUCTURE_3ejb| PDB=3ejb | SCENE= }}
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==Crystal Structure of P450BioI in complex with tetradecanoic acid ligated Acyl Carrier Protein==
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<StructureSection load='3ejb' size='340' side='right'caption='[[3ejb]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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===Crystal Structure of P450BioI in complex with tetradecanoic acid ligated Acyl Carrier Protein===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3ejb]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis] and [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EJB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EJB FirstGlance]. <br>
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{{ABSTRACT_PUBMED_18838690}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=HTG:HEPTYL+1-THIOHEXOPYRANOSIDE'>HTG</scene>, <scene name='pdbligand=ZMP:S-[2-({N-[(2S)-2-HYDROXY-3,3-DIMETHYL-4-(PHOSPHONOOXY)BUTANOYL]-BETA-ALANYL}AMINO)ETHYL]+TETRADECANETHIOATE'>ZMP</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ejb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ejb OCA], [https://pdbe.org/3ejb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ejb RCSB], [https://www.ebi.ac.uk/pdbsum/3ejb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ejb ProSAT]</span></td></tr>
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[[3ejb]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis] and [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EJB OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ACP_ECOLI ACP_ECOLI] Carrier of the growing fatty acid chain in fatty acid biosynthesis.[HAMAP-Rule:MF_01217]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ej/3ejb_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ejb ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Fatty acid synthase|Fatty acid synthase]]
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*[[Acyl carrier protein 3D structures|Acyl carrier protein 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:018838690</ref><references group="xtra"/>
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[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Escherichia coli]]
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[[Category: Escherichia coli K-12]]
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[[Category: Cryle, M J.]]
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[[Category: Large Structures]]
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[[Category: Schlichting, I.]]
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[[Category: Cryle MJ]]
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[[Category: 4-helix bundle]]
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[[Category: Schlichting I]]
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[[Category: Biotin biosynthesis]]
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[[Category: Carrier protein]]
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[[Category: Cytochrome p450 fold]]
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[[Category: Fatty acid biosynthesis]]
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[[Category: Heme]]
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[[Category: Iron]]
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[[Category: Lipid synthesis]]
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[[Category: Metal-binding]]
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[[Category: Monooxygenase]]
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[[Category: Oxidoreductase]]
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[[Category: Oxidoreductase-lipid transport complex]]
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[[Category: Phosphopantetheine]]
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[[Category: Protein-protein complex]]
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Current revision

Crystal Structure of P450BioI in complex with tetradecanoic acid ligated Acyl Carrier Protein

PDB ID 3ejb

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