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3exw

From Proteopedia

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{{Seed}}
 
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[[Image:3exw.png|left|200px]]
 
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<!--
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==Crystal structure of the human Adenovirus type 7 fiber knob==
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The line below this paragraph, containing "STRUCTURE_3exw", creates the "Structure Box" on the page.
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<StructureSection load='3exw' size='340' side='right'caption='[[3exw]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3exw]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_adenovirus_7 Human adenovirus 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EXW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EXW FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3exw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3exw OCA], [https://pdbe.org/3exw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3exw RCSB], [https://www.ebi.ac.uk/pdbsum/3exw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3exw ProSAT]</span></td></tr>
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{{STRUCTURE_3exw| PDB=3exw | SCENE= }}
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</table>
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== Function ==
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===Crystal structure of the human Adenovirus type 7 fiber knob===
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[https://www.uniprot.org/uniprot/SPIKE_ADE07 SPIKE_ADE07] Forms spikes that protrude from each vertex of the icosahedral capsid. Interacts with host receptor CD46 to provide virion initial attachment to target cell. Fiber proteins are shed during virus entry, when virus is still at the cell surface.<ref>PMID:11152512</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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<!--
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_18987134}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 18987134 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ex/3exw_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_18987134}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3exw ConSurf].
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3EXW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_adenovirus_7 Human adenovirus 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EXW OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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An arginine switch in the species B adenovirus knob determines high-affinity engagement of the cellular receptor CD46., Persson BD, Muller S, Reiter DM, Schmitt BB, Marttila M, Sumowski CV, Schweizer S, Scheu U, Ochsenfeld C, Arnberg N, Stehle T, J Virol. 2008 Nov 5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18987134 18987134]
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__TOC__
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</StructureSection>
[[Category: Human adenovirus 7]]
[[Category: Human adenovirus 7]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
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[[Category: Arnberg N]]
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[[Category: Ad7]]
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[[Category: Persson BD]]
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[[Category: Adenovirus]]
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[[Category: Reiter DM]]
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[[Category: Ad]]
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[[Category: Stehle T]]
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[[Category: Fiber knob]]
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[[Category: Trimer]]
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[[Category: Viral protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 14 20:28:56 2009''
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Current revision

Crystal structure of the human Adenovirus type 7 fiber knob

PDB ID 3exw

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