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3ga4

From Proteopedia

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{{Seed}}
 
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[[Image:3ga4.png|left|200px]]
 
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==Crystal structure of Ost6L (photoreduced form)==
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The line below this paragraph, containing "STRUCTURE_3ga4", creates the "Structure Box" on the page.
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<StructureSection load='3ga4' size='340' side='right'caption='[[3ga4]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3ga4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GA4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GA4 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
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{{STRUCTURE_3ga4| PDB=3ga4 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ga4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ga4 OCA], [https://pdbe.org/3ga4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ga4 RCSB], [https://www.ebi.ac.uk/pdbsum/3ga4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ga4 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/OST6_YEAST OST6_YEAST] Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Can participate in redox reactions and is able to catalyze dithiol-disulfide exchange reactions with other proteins, albeit with relatively low efficiency. May form transient disulfide bonds with nascent polypeptides in the endoplasmic reticulum and thereby promote efficient glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal oligosaccharyl transferase activity.<ref>PMID:19549845</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ga/3ga4_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ga4 ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of Ost6L (photoreduced form)===
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==See Also==
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*[[Glycosyltransferase 3D structures|Glycosyltransferase 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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3GA4 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GA4 OCA].
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__TOC__
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[[Category: Dolichyl-diphosphooligosaccharide--protein glycotransferase]]
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Aebi, M.]]
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[[Category: Aebi M]]
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[[Category: Brozzo, M S.]]
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[[Category: Brozzo MS]]
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[[Category: Capitani, G.]]
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[[Category: Capitani G]]
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[[Category: Fritsch, F.]]
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[[Category: Fritsch F]]
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[[Category: Glockshuber, R.]]
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[[Category: Glockshuber R]]
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[[Category: Grimshaw, J P.A.]]
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[[Category: Grimshaw JPA]]
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[[Category: Gruetter, M G.]]
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[[Category: Gruetter MG]]
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[[Category: Schulz, B L.]]
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[[Category: Schulz BL]]
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[[Category: Stirnimann, C U.]]
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[[Category: Stirnimann CU]]
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[[Category: Active site loop]]
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[[Category: Membrane]]
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[[Category: Oxidoreductase]]
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[[Category: Redox state]]
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[[Category: Transferase]]
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[[Category: Transmembrane]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 22 20:22:13 2009''
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Current revision

Crystal structure of Ost6L (photoreduced form)

PDB ID 3ga4

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