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3lob

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[[Image:3lob.png|left|200px]]
 
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==Crystal Structure of Flock House Virus calcium mutant==
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The line below this paragraph, containing "STRUCTURE_3lob", creates the "Structure Box" on the page.
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<StructureSection load='3lob' size='340' side='right'caption='[[3lob]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3lob]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Flock_House_virus Flock House virus] and [https://en.wikipedia.org/wiki/Spodoptera_frugiperda Spodoptera frugiperda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LOB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LOB FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P:2-DEOXY-N1,N2-PROPANO+GUANOSINE+MONOPHOSPHATE'>P</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_3lob| PDB=3lob | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lob OCA], [https://pdbe.org/3lob PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lob RCSB], [https://www.ebi.ac.uk/pdbsum/3lob PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lob ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CAPSD_FHV CAPSD_FHV] Capsid protein alpha self-assembles to form an icosahedral procapsid with a T=3 symmetry, about 30 nm in diameter, and consisting of 60 capsid proteins trimers. In addition, 240 calcium ions are incorporated per capsid during assembly. The capsid encapsulates the two genomic RNAs. Capsid maturation occurs via autoproteolytic cleavage of capsid protein alpha generating capsid protein beta and the membrane-active peptide gamma. Peptide gamma: membrane-permeabilizing peptide produced by virus maturation, thereby creating the infectious virion. After endocytosis into the host cell, peptide gamma is probably exposed in endosomes, where it permeabilizes the endosomal membrane, facilitating translocation of viral capsid or RNA into the cytoplasm (Probable).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lo/3lob_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lob ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure of Flock House Virus calcium mutant===
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==See Also==
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*[[Flock house virus protein B2|Flock house virus protein B2]]
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*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
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__TOC__
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 20164221 is the PubMed ID number.
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[[Category: Flock House virus]]
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_20164221}}
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==About this Structure==
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[[3lob]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Flock_house_virus Flock house virus] and [http://en.wikipedia.org/wiki/Spodoptera_frugiperda Spodoptera frugiperda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LOB OCA].
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==Reference==
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<ref group="xtra">PMID:20164221</ref><references group="xtra"/>
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[[Category: Flock house virus]]
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[[Category: Nodavirus endopeptidase]]
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[[Category: Spodoptera frugiperda]]
[[Category: Spodoptera frugiperda]]
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[[Category: Banerjee, M.]]
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[[Category: Banerjee M]]
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[[Category: Huang, R.]]
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[[Category: Huang R]]
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[[Category: Johnson, J E.]]
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[[Category: Johnson JE]]
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[[Category: Speir, J A.]]
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[[Category: Speir JA]]
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[[Category: Aspartyl protease]]
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[[Category: Beta-barrel]]
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[[Category: Capsid protein]]
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[[Category: Flock house virus]]
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[[Category: Hydrolase]]
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[[Category: Icosahedral virus]]
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[[Category: Jellyroll]]
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[[Category: Protease]]
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[[Category: Rna]]
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[[Category: Virion]]
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[[Category: Virus]]
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Current revision

Crystal Structure of Flock House Virus calcium mutant

PDB ID 3lob

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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