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3mc6

From Proteopedia

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{{Seed}}
 
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[[Image:3mc6.jpg|left|200px]]
 
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<!--
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==Crystal structure of ScDPL1==
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The line below this paragraph, containing "STRUCTURE_3mc6", creates the "Structure Box" on the page.
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<StructureSection load='3mc6' size='340' side='right'caption='[[3mc6]], [[Resolution|resolution]] 3.15&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3mc6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MC6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MC6 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.15&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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{{STRUCTURE_3mc6| PDB=3mc6 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mc6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mc6 OCA], [https://pdbe.org/3mc6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mc6 RCSB], [https://www.ebi.ac.uk/pdbsum/3mc6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mc6 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SGPL_YEAST SGPL_YEAST] Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine.<ref>PMID:20696404</ref> <ref>PMID:9334171</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mc/3mc6_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3mc6 ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of ScDPL1===
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==See Also==
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*[[Aldolase 3D structures|Aldolase 3D structures]]
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== References ==
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<!--
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_20696404}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 20696404 is the PubMed ID number.
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</StructureSection>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_20696404}}
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==About this Structure==
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3MC6 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MC6 OCA].
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==Reference==
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<ref group="xtra">PMID:20696404</ref><references group="xtra"/>
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[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Sphinganine-1-phosphate aldolase]]
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[[Category: Bourquin F]]
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[[Category: Bourquin, F.]]
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[[Category: Capitani G]]
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[[Category: Capitani, G.]]
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[[Category: Grutter MG]]
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[[Category: Grutter, M G.]]
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[[Category: Carboxy-lyase activity]]
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[[Category: Lyase]]
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[[Category: Pyridoxyl phosphate]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 18 11:45:20 2010''
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Current revision

Crystal structure of ScDPL1

PDB ID 3mc6

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OCA

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