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3rtx
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3rtx is ON HOLD Authors: Ghosh, A., Lima, C.D. Description: Crystal structure of mammalian capping enzyme (Mce1) and Pol II CTD complex) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of mammalian capping enzyme (Mce1) and Pol II CTD complex== | |
| - | + | <StructureSection load='3rtx' size='340' side='right'caption='[[3rtx]], [[Resolution|resolution]] 2.81Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3rtx]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RTX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RTX FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.81Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GUN:GUANINE'>GUN</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rtx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rtx OCA], [https://pdbe.org/3rtx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rtx RCSB], [https://www.ebi.ac.uk/pdbsum/3rtx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rtx ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MCE1_MOUSE MCE1_MOUSE] Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Ghosh A]] | ||
| + | [[Category: Lima CD]] | ||
Current revision
Crystal structure of mammalian capping enzyme (Mce1) and Pol II CTD complex
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