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4f0w

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'''Unreleased structure'''
 
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The entry 4f0w is ON HOLD until Paper Publication
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==Crystal structure of type effector Tse1 C30A mutant from Pseudomonas aeruginousa==
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<StructureSection load='4f0w' size='340' side='right'caption='[[4f0w]], [[Resolution|resolution]] 1.24&Aring;' scene=''>
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Authors: Zhang, H., Gao, Z.Q., Dong, Y.H.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4f0w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F0W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F0W FirstGlance]. <br>
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Description: Crystal structure of type effector Tse1 C30A mutant from Pseudomonas aeruginousa
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.24&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f0w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f0w OCA], [https://pdbe.org/4f0w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f0w RCSB], [https://www.ebi.ac.uk/pdbsum/4f0w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f0w ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TSE1_PSEAE TSE1_PSEAE] Toxin secreted by the H1 type VI (H1-T6SS) secretion system into the periplasm of recipient cells. Degrades peptidoglycan via amidase activity thereby helping itself to compete with other bacteria (PubMed:21776080, PubMed:22931054, PubMed:22813741, PubMed:22700987). To protect itself, the bacterium synthesizes immunity protein Tsi1 that specifically interacts with and inactivates cognate toxin (PubMed:21776080, PubMed:22931054, PubMed:22700987).<ref>PMID:21776080</ref> <ref>PMID:22700987</ref> <ref>PMID:22813741</ref> <ref>PMID:22931054</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Pseudomonas aeruginosa PAO1]]
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[[Category: Dong YH]]
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[[Category: Gao ZQ]]
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[[Category: Zhang H]]

Current revision

Crystal structure of type effector Tse1 C30A mutant from Pseudomonas aeruginousa

PDB ID 4f0w

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