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4fao
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| - | [[Image:4fao.jpg|left|200px]] | ||
| - | + | ==Specificity and Structure of a high affinity Activin-like 1 (ALK1) signaling complex== | |
| + | <StructureSection load='4fao' size='340' side='right'caption='[[4fao]], [[Resolution|resolution]] 3.36Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4fao]] is a 36 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FAO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FAO FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.357Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fao FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fao OCA], [https://pdbe.org/4fao PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fao RCSB], [https://www.ebi.ac.uk/pdbsum/4fao PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fao ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GDF2_HUMAN GDF2_HUMAN] Potent circulating inhibitor of angiogenesis. Could be involved in bone formation. Signals through the type I activin receptor ACVRL1 but not other Alks.<ref>PMID:18309101</ref> <ref>PMID:22799562</ref> | ||
| - | == | + | ==See Also== |
| - | + | *[[Growth differentiation factor 3D STRUCTURES|Growth differentiation factor 3D STRUCTURES]] | |
| - | + | == References == | |
| - | == | + | <references/> |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Greppi | + | [[Category: Large Structures]] |
| - | [[Category: Grinberg | + | [[Category: Greppi C]] |
| - | [[Category: Kumar | + | [[Category: Grinberg AV]] |
| - | [[Category: Liharska | + | [[Category: Kumar R]] |
| - | [[Category: Liu | + | [[Category: Liharska K]] |
| - | [[Category: Lowden | + | [[Category: Liu J]] |
| - | [[Category: Martinez-Hackert | + | [[Category: Lowden P]] |
| - | [[Category: Sako | + | [[Category: Martinez-Hackert E]] |
| - | [[Category: Seehra | + | [[Category: Sako D]] |
| - | [[Category: Townson | + | [[Category: Seehra J]] |
| - | [[Category: Ucran | + | [[Category: Townson SA]] |
| - | [[Category: Underwood | + | [[Category: Ucran JA]] |
| - | + | [[Category: Underwood KW]] | |
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Current revision
Specificity and Structure of a high affinity Activin-like 1 (ALK1) signaling complex
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Categories: Homo sapiens | Large Structures | Greppi C | Grinberg AV | Kumar R | Liharska K | Liu J | Lowden P | Martinez-Hackert E | Sako D | Seehra J | Townson SA | Ucran JA | Underwood KW
