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4l9q

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'''Unreleased structure'''
 
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The entry 4l9q is ON HOLD
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==X-ray study of human serum albumin complexed with teniposide==
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<StructureSection load='4l9q' size='340' side='right'caption='[[4l9q]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4l9q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L9Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4L9Q FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9TP:(5S,5AR,8AR,9R)-9-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-8-OXO-5,5A,6,8,8A,9-HEXAHYDROFURO[3,4 6,7]NAPHTHO[2,3-D][1,3]DIOXOL-5-YL+4,6-O-(THIOPHEN-2-YLMETHYLIDENE)-BETA-D-GLUCOPYRANOSIDE'>9TP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4l9q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l9q OCA], [https://pdbe.org/4l9q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4l9q RCSB], [https://www.ebi.ac.uk/pdbsum/4l9q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4l9q ProSAT]</span></td></tr>
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</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN] Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:[https://omim.org/entry/103600 103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.<ref>PMID:8048949</ref> <ref>PMID:7852505</ref> <ref>PMID:9329347</ref> <ref>PMID:9589637</ref>
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== Function ==
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[https://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.<ref>PMID:19021548</ref>
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Authors: Wang, Z., Ho, J.X., Ruble, J., Rose, J.P., Carter, D.C.
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==See Also==
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*[[Albumin 3D structures|Albumin 3D structures]]
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Description: X-ray study of human serum albumin complexed with teniposide
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Carter DC]]
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[[Category: Ho JX]]
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[[Category: Rose JP]]
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[[Category: Ruble J]]
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[[Category: Wang Z]]

Current revision

X-ray study of human serum albumin complexed with teniposide

PDB ID 4l9q

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