This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4s2t
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4s2t is ON HOLD Authors: Iyer, S., La-Borde, P., Payne, K.A.P., Parsons, M.R., Turner, A.J., Isaac, R.E., Acharya, K.R. Description: Crystal struct...) |
|||
| (7 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of X-prolyl aminopeptidase from Caenorhabditis elegans: a cytosolic enzyme with a di-nuclear active site== | |
| + | <StructureSection load='4s2t' size='340' side='right'caption='[[4s2t]], [[Resolution|resolution]] 2.15Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4s2t]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4S2T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4S2T FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=01B:(2S,3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTANOIC+ACID'>01B</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4s2t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4s2t OCA], [https://pdbe.org/4s2t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4s2t RCSB], [https://www.ebi.ac.uk/pdbsum/4s2t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4s2t ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/XPP_CAEEL XPP_CAEEL] Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro (PubMed:11606206, PubMed:25905034). Has activity towards the flp-9 neuropeptide KPSFVRF-amide (PubMed:11606206).<ref>PMID:11606206</ref> <ref>PMID:25905034</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Caenorhabditis elegans]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Acharya KR]] |
| - | [[Category: | + | [[Category: Isaac RE]] |
| - | [[Category: | + | [[Category: Iyer S]] |
| + | [[Category: La-Borde P]] | ||
| + | [[Category: Parsons MR]] | ||
| + | [[Category: Payne KAP]] | ||
| + | [[Category: Turner AJ]] | ||
Current revision
Crystal structure of X-prolyl aminopeptidase from Caenorhabditis elegans: a cytosolic enzyme with a di-nuclear active site
| |||||||||||
