5lkd
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of the Xi glutathione transferase ECM4 from Saccharomyces cerevisiae in complex with glutathione== | |
+ | <StructureSection load='5lkd' size='340' side='right'caption='[[5lkd]], [[Resolution|resolution]] 1.68Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[5lkd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LKD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LKD FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.68Å</td></tr> | ||
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lkd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lkd OCA], [https://pdbe.org/5lkd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lkd RCSB], [https://www.ebi.ac.uk/pdbsum/5lkd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lkd ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/GTO2_YEAST GTO2_YEAST] Active as '1-Cys' thiol transferase against beta-hydroxyethyl disulfide (HED), as dehydroascorbate reductase and as dimethylarsinic acid reductase, while not active against the standard GST substrate 1-chloro-2,4-dinitrobenzene (CDNB). May be involved in cell wall organization and biogenesis.<ref>PMID:16709151</ref> | ||
- | + | ==See Also== | |
- | + | *[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]] | |
- | + | == References == | |
- | [[Category: | + | <references/> |
- | [[Category: | + | __TOC__ |
- | [[Category: | + | </StructureSection> |
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: | + | [[Category: Saccharomyces cerevisiae S288C]] |
- | [[Category: | + | [[Category: Didierjean C]] |
- | [[Category: | + | [[Category: Favier F]] |
- | [[Category: | + | [[Category: Gelhaye E]] |
+ | [[Category: Girardet JM]] | ||
+ | [[Category: Hecker A]] | ||
+ | [[Category: Morel-Rouhier M]] | ||
+ | [[Category: Schwartz M]] |
Current revision
Crystal structure of the Xi glutathione transferase ECM4 from Saccharomyces cerevisiae in complex with glutathione
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