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7fx2
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7fx2 is ON HOLD Authors: Ehler, A., Benz, J., Obst, U., Richter, H., Rudolph, M.G. Description: Crystal Structure of human FABP4 binding site mutat...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of human FABP4 binding site mutated to that of FABP5 in complex with 2-[[6,6-difluoro-3-(4-methyl-1,3-thiazol-2-yl)-5,7-dihydro-4H-1-benzothiophen-2-yl]carbamoyl]cyclohexene-1-carboxylic acid== | |
| - | + | <StructureSection load='7fx2' size='340' side='right'caption='[[7fx2]], [[Resolution|resolution]] 1.47Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7fx2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FX2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FX2 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.47Å</td></tr> | |
| - | [[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=QJQ:2-{[(3M)-6,6-difluoro-3-(4-methyl-1,3-thiazol-2-yl)-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]carbamoyl}cyclohex-1-ene-1-carboxylic+acid'>QJQ</scene></td></tr> |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fx2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fx2 OCA], [https://pdbe.org/7fx2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fx2 RCSB], [https://www.ebi.ac.uk/pdbsum/7fx2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fx2 ProSAT]</span></td></tr> |
| - | [[ | + | </table> |
| - | [[Category: Benz | + | == Function == |
| - | [[Category: Obst | + | [https://www.uniprot.org/uniprot/FABP4_HUMAN FABP4_HUMAN] Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus (By similarity). |
| - | [[Category: Rudolph | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Benz J]] | ||
| + | [[Category: Ehler A]] | ||
| + | [[Category: Obst U]] | ||
| + | [[Category: Richter H]] | ||
| + | [[Category: Rudolph MG]] | ||
Current revision
Crystal Structure of human FABP4 binding site mutated to that of FABP5 in complex with 2-[[6,6-difluoro-3-(4-methyl-1,3-thiazol-2-yl)-5,7-dihydro-4H-1-benzothiophen-2-yl]carbamoyl]cyclohexene-1-carboxylic acid
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Categories: Homo sapiens | Large Structures | Benz J | Ehler A | Obst U | Richter H | Rudolph MG
