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7g0e
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7g0e is ON HOLD Authors: Ehler, A., Benz, J., Obst, U., Ceccarelli-Simona, M., Rudolph, M.G. Description: Crystal Structure of human FABP5 in compl...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of human FABP5 in complex with 2-[(3-ethoxycarbonyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)carbamoyl]cyclopentene-1-carboxylic acid== | |
| - | + | <StructureSection load='7g0e' size='340' side='right'caption='[[7g0e]], [[Resolution|resolution]] 1.11Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7g0e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7G0E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7G0E FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.11Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=L8T:2-{[3-(ethoxycarbonyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]carbamoyl}cyclopent-1-ene-1-carboxylic+acid'>L8T</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7g0e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7g0e OCA], [https://pdbe.org/7g0e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7g0e RCSB], [https://www.ebi.ac.uk/pdbsum/7g0e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7g0e ProSAT]</span></td></tr> |
| - | [[Category: Benz | + | </table> |
| - | [[Category: Ceccarelli-Simona | + | == Function == |
| - | [[Category: Obst | + | [https://www.uniprot.org/uniprot/FABP5_HUMAN FABP5_HUMAN] High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation. |
| - | [[Category: Rudolph | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Benz J]] | ||
| + | [[Category: Ceccarelli-Simona M]] | ||
| + | [[Category: Ehler A]] | ||
| + | [[Category: Obst U]] | ||
| + | [[Category: Rudolph MG]] | ||
Current revision
Crystal Structure of human FABP5 in complex with 2-[(3-ethoxycarbonyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)carbamoyl]cyclopentene-1-carboxylic acid
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