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From Proteopedia
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| - | ==== | + | ==Crystal structure of the complex of CD16A bound by an anti-CD16A Fab== |
| - | <StructureSection load='7seg' size='340' side='right'caption='[[7seg]]' scene=''> | + | <StructureSection load='7seg' size='340' side='right'caption='[[7seg]], [[Resolution|resolution]] 2.16Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7seg]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7SEG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7SEG FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7seg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7seg OCA], [https://pdbe.org/7seg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7seg RCSB], [https://www.ebi.ac.uk/pdbsum/7seg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7seg ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.156Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7seg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7seg OCA], [https://pdbe.org/7seg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7seg RCSB], [https://www.ebi.ac.uk/pdbsum/7seg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7seg ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/FCG3A_HUMAN FCG3A_HUMAN] The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23006327</ref> <ref>PMID:8608639</ref> <ref>PMID:8609432</ref> <ref>PMID:8874200</ref> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FCG3A_HUMAN FCG3A_HUMAN] Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.<ref>PMID:21768335</ref> <ref>PMID:22023369</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Antibody 3D structures|Antibody 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Kiefer JR]] |
| + | [[Category: Polson AG]] | ||
| + | [[Category: Wallweber HA]] | ||
Current revision
Crystal structure of the complex of CD16A bound by an anti-CD16A Fab
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