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8e22
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==VPS37A_21-148== | |
| + | <StructureSection load='8e22' size='340' side='right'caption='[[8e22]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[8e22]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8E22 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8E22 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8e22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8e22 OCA], [https://pdbe.org/8e22 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8e22 RCSB], [https://www.ebi.ac.uk/pdbsum/8e22 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8e22 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/VP37A_HUMAN VP37A_HUMAN] Autosomal recessive spastic paraplegia type 53. The disease is caused by variants affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/VP37A_HUMAN VP37A_HUMAN] Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.<ref>PMID:15240819</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Vacuolar protein sorting-associated protein 3D structures|Vacuolar protein sorting-associated protein 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: Tian | + | </StructureSection> |
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Tian F]] | ||
| + | [[Category: Ye YS]] | ||
Current revision
VPS37A_21-148
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