This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1i2w

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:44, 3 April 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1i2w.png|left|200px]]
 
-
{{STRUCTURE_1i2w| PDB=1i2w | SCENE= }}
+
==BETA-LACTAMASE FROM BACILLUS LICHENIFORMIS BS3 COMPLEXED WITH CEFOXITIN==
-
 
+
<StructureSection load='1i2w' size='340' side='right'caption='[[1i2w]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
-
===BETA-LACTAMASE FROM BACILLUS LICHENIFORMIS BS3 COMPLEXED WITH CEFOXITIN===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[1i2w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_licheniformis Bacillus licheniformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I2W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I2W FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_11827533}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1QL:(2R)-5-[(carbamoyloxy)methyl]-2-{(1S)-1-methoxy-2-oxo-1-[(thiophen-2-ylacetyl)amino]ethyl}-3,6-dihydro-2H-1,3-thiazine-4-carboxylic+acid'>1QL</scene>, <scene name='pdbligand=OUT:CARBAMIC+ACID'>OUT</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i2w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i2w OCA], [https://pdbe.org/1i2w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i2w RCSB], [https://www.ebi.ac.uk/pdbsum/1i2w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i2w ProSAT]</span></td></tr>
-
[[1i2w]] is a 2 chain structure of [[Beta-lactamase]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_licheniformis Bacillus licheniformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I2W OCA].
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/BLAC_BACLI BLAC_BACLI]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i2/1i2w_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1i2w ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
-
*[[Beta-lactamase|Beta-lactamase]]
+
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
-
 
+
__TOC__
-
==Reference==
+
</StructureSection>
-
<ref group="xtra">PMID:011827533</ref><references group="xtra"/>
+
[[Category: Bacillus licheniformis]]
[[Category: Bacillus licheniformis]]
-
[[Category: Beta-lactamase]]
+
[[Category: Large Structures]]
-
[[Category: Charlier, P.]]
+
[[Category: Charlier P]]
-
[[Category: Dive, G.]]
+
[[Category: Dive G]]
-
[[Category: Fonze, E.]]
+
[[Category: Fonze E]]
-
[[Category: Frere, J M.]]
+
[[Category: Frere JM]]
-
[[Category: Sauvage, E.]]
+
[[Category: Sauvage E]]
-
[[Category: Vanhove, M.]]
+
[[Category: Vanhove M]]
-
[[Category: Antibiotic resistance]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Serine beta-lactamase]]
+

Current revision

BETA-LACTAMASE FROM BACILLUS LICHENIFORMIS BS3 COMPLEXED WITH CEFOXITIN

PDB ID 1i2w

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools