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1i2w

From Proteopedia

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{{Seed}}
 
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[[Image:1i2w.png|left|200px]]
 
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==BETA-LACTAMASE FROM BACILLUS LICHENIFORMIS BS3 COMPLEXED WITH CEFOXITIN==
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The line below this paragraph, containing "STRUCTURE_1i2w", creates the "Structure Box" on the page.
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<StructureSection load='1i2w' size='340' side='right'caption='[[1i2w]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1i2w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_licheniformis Bacillus licheniformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I2W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I2W FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1QL:(2R)-5-[(carbamoyloxy)methyl]-2-{(1S)-1-methoxy-2-oxo-1-[(thiophen-2-ylacetyl)amino]ethyl}-3,6-dihydro-2H-1,3-thiazine-4-carboxylic+acid'>1QL</scene>, <scene name='pdbligand=OUT:CARBAMIC+ACID'>OUT</scene></td></tr>
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{{STRUCTURE_1i2w| PDB=1i2w | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i2w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i2w OCA], [https://pdbe.org/1i2w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i2w RCSB], [https://www.ebi.ac.uk/pdbsum/1i2w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i2w ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BLAC_BACLI BLAC_BACLI]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i2/1i2w_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1i2w ConSurf].
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<div style="clear:both"></div>
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===BETA-LACTAMASE FROM BACILLUS LICHENIFORMIS BS3 COMPLEXED WITH CEFOXITIN===
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==See Also==
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*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_11827533}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 11827533 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11827533}}
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==About this Structure==
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1I2W is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_licheniformis Bacillus licheniformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I2W OCA].
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==Reference==
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Crystal structures of the Bacillus licheniformis BS3 class A beta-lactamase and of the acyl-enzyme adduct formed with cefoxitin., Fonze E, Vanhove M, Dive G, Sauvage E, Frere JM, Charlier P, Biochemistry. 2002 Feb 12;41(6):1877-85. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11827533 11827533]
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[[Category: Bacillus licheniformis]]
[[Category: Bacillus licheniformis]]
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[[Category: Beta-lactamase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Charlier P]]
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[[Category: Charlier, P.]]
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[[Category: Dive G]]
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[[Category: Dive, G.]]
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[[Category: Fonze E]]
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[[Category: Fonze, E.]]
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[[Category: Frere JM]]
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[[Category: Frere, J M.]]
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[[Category: Sauvage E]]
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[[Category: Sauvage, E.]]
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[[Category: Vanhove M]]
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[[Category: Vanhove, M.]]
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[[Category: Antibiotic resistance]]
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[[Category: Hydrolase]]
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[[Category: Serine beta-lactamase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 10:19:45 2008''
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Current revision

BETA-LACTAMASE FROM BACILLUS LICHENIFORMIS BS3 COMPLEXED WITH CEFOXITIN

PDB ID 1i2w

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