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1i8b

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{{Seed}}
 
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[[Image:1i8b.png|left|200px]]
 
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==Chalcone synthase (G256F)==
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The line below this paragraph, containing "STRUCTURE_1i8b", creates the "Structure Box" on the page.
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<StructureSection load='1i8b' size='340' side='right'caption='[[1i8b]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1i8b]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Medicago_sativa Medicago sativa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I8B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I8B FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr>
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{{STRUCTURE_1i8b| PDB=1i8b | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i8b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i8b OCA], [https://pdbe.org/1i8b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i8b RCSB], [https://www.ebi.ac.uk/pdbsum/1i8b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i8b ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CHS2_MEDSA CHS2_MEDSA] The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.<ref>PMID:10653632</ref> <ref>PMID:11732902</ref> <ref>PMID:11959984</ref> <ref>PMID:15380179</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i8/1i8b_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1i8b ConSurf].
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<div style="clear:both"></div>
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===CHALCONE SYNTHASE (G256F)===
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==See Also==
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*[[Chalcone synthase|Chalcone synthase]]
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_11732902}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 11732902 is the PubMed ID number.
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</StructureSection>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_11732902}}
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==About this Structure==
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1I8B is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Medicago_sativa Medicago sativa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I8B OCA].
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==Reference==
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Structure-guided programming of polyketide chain-length determination in chalcone synthase., Jez JM, Bowman ME, Noel JP, Biochemistry. 2001 Dec 11;40(49):14829-38. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11732902 11732902]
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[[Category: Medicago sativa]]
[[Category: Medicago sativa]]
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[[Category: Naringenin-chalcone synthase]]
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[[Category: Bowman ME]]
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[[Category: Single protein]]
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[[Category: Jez JM]]
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[[Category: Bowman, M E.]]
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[[Category: Noel JP]]
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[[Category: Jez, J M.]]
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[[Category: Noel, J P.]]
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[[Category: Chalcone synthase]]
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[[Category: Polyketide synthase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 10:34:33 2008''
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Current revision

Chalcone synthase (G256F)

PDB ID 1i8b

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