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1im8
From Proteopedia
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| - | [[Image:1im8.png|left|200px]] | ||
| - | + | ==Crystal structure of YecO from Haemophilus influenzae (HI0319), a methyltransferase with a bound S-adenosylhomocysteine== | |
| + | <StructureSection load='1im8' size='340' side='right'caption='[[1im8]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1im8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae_Rd_KW20 Haemophilus influenzae Rd KW20]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IM8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IM8 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SAI:S-ADENOSYL-L-HOMOSELENOCYSTEINE'>SAI</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1im8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1im8 OCA], [https://pdbe.org/1im8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1im8 RCSB], [https://www.ebi.ac.uk/pdbsum/1im8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1im8 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CMOA_HAEIN CMOA_HAEIN] Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity). | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/im/1im8_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1im8 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[TRNA methyltransferase 3D structures|TRNA methyltransferase 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Haemophilus influenzae Rd KW20]] | |
| - | [[ | + | [[Category: Large Structures]] |
| - | + | [[Category: Bonander N]] | |
| - | + | [[Category: Eisenstein E]] | |
| - | + | [[Category: Herzberg O]] | |
| - | [[Category: Haemophilus influenzae | + | [[Category: Howard A]] |
| - | [[Category: Bonander | + | [[Category: Lim K]] |
| - | [[Category: Eisenstein | + | [[Category: Tempczyk A]] |
| - | [[Category: Herzberg | + | [[Category: Toedt J]] |
| - | [[Category: Howard | + | [[Category: Zhang H]] |
| - | [[Category: Lim | + | |
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| - | [[Category: Tempczyk | + | |
| - | [[Category: Toedt | + | |
| - | [[Category: Zhang | + | |
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Current revision
Crystal structure of YecO from Haemophilus influenzae (HI0319), a methyltransferase with a bound S-adenosylhomocysteine
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