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1im8

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{{Seed}}
 
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[[Image:1im8.png|left|200px]]
 
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==Crystal structure of YecO from Haemophilus influenzae (HI0319), a methyltransferase with a bound S-adenosylhomocysteine==
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The line below this paragraph, containing "STRUCTURE_1im8", creates the "Structure Box" on the page.
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<StructureSection load='1im8' size='340' side='right'caption='[[1im8]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1im8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae_Rd_KW20 Haemophilus influenzae Rd KW20]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IM8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IM8 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SAI:S-ADENOSYL-L-HOMOSELENOCYSTEINE'>SAI</scene></td></tr>
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{{STRUCTURE_1im8| PDB=1im8 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1im8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1im8 OCA], [https://pdbe.org/1im8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1im8 RCSB], [https://www.ebi.ac.uk/pdbsum/1im8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1im8 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CMOA_HAEIN CMOA_HAEIN] Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/im/1im8_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1im8 ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of YecO from Haemophilus influenzae (HI0319), a methyltransferase with a bound S-adenosylhomocysteine===
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==See Also==
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*[[TRNA methyltransferase 3D structures|TRNA methyltransferase 3D structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_11746687}}, adds the Publication Abstract to the page
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[[Category: Haemophilus influenzae Rd KW20]]
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(as it appears on PubMed at http://www.pubmed.gov), where 11746687 is the PubMed ID number.
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[[Category: Large Structures]]
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[[Category: Bonander N]]
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{{ABSTRACT_PUBMED_11746687}}
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[[Category: Eisenstein E]]
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[[Category: Herzberg O]]
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==About this Structure==
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[[Category: Howard A]]
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1IM8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IM8 OCA].
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[[Category: Lim K]]
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[[Category: Tempczyk A]]
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==Reference==
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[[Category: Toedt J]]
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Crystal structure of YecO from Haemophilus influenzae (HI0319) reveals a methyltransferase fold and a bound S-adenosylhomocysteine., Lim K, Zhang H, Tempczyk A, Bonander N, Toedt J, Howard A, Eisenstein E, Herzberg O, Proteins. 2001 Dec 1;45(4):397-407. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11746687 11746687]
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[[Category: Zhang H]]
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[[Category: Haemophilus influenzae]]
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[[Category: Single protein]]
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[[Category: Bonander, N.]]
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[[Category: Eisenstein, E.]]
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[[Category: Herzberg, O.]]
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[[Category: Howard, A.]]
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[[Category: Lim, K.]]
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[[Category: S2F, Structure 2.Function Project.]]
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[[Category: Tempczyk, A.]]
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[[Category: Toedt, J.]]
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[[Category: Zhang, H.]]
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[[Category: Adenosylhomocysteine]]
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[[Category: Hypothetical protein]]
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[[Category: Methyltransferase]]
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[[Category: S2f]]
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[[Category: Structural genomic]]
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[[Category: Structure 2 function project]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 13:31:40 2008''
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Current revision

Crystal structure of YecO from Haemophilus influenzae (HI0319), a methyltransferase with a bound S-adenosylhomocysteine

PDB ID 1im8

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