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1itf

From Proteopedia

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{{Seed}}
 
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[[Image:1itf.png|left|200px]]
 
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==INTERFERON ALPHA-2A, NMR, 24 STRUCTURES==
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The line below this paragraph, containing "STRUCTURE_1itf", creates the "Structure Box" on the page.
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<StructureSection load='1itf' size='340' side='right'caption='[[1itf]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1itf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The August 2010 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Interferons'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2010_8 10.2210/rcsb_pdb/mom_2010_8]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ITF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ITF FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1itf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1itf OCA], [https://pdbe.org/1itf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1itf RCSB], [https://www.ebi.ac.uk/pdbsum/1itf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1itf ProSAT]</span></td></tr>
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{{STRUCTURE_1itf| PDB=1itf | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/IFNA2_HUMAN IFNA2_HUMAN] Produced by macrophages, IFN-alpha have antiviral activities.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/it/1itf_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1itf ConSurf].
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<div style="clear:both"></div>
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===INTERFERON ALPHA-2A, NMR, 24 STRUCTURES===
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==See Also==
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*[[Interferon 3D structures|Interferon 3D structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_9417943}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 9417943 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9417943}}
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==About this Structure==
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1ITF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ITF OCA].
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==Reference==
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The three-dimensional high resolution structure of human interferon alpha-2a determined by heteronuclear NMR spectroscopy in solution., Klaus W, Gsell B, Labhardt AM, Wipf B, Senn H, J Mol Biol. 1997 Dec 12;274(4):661-75. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9417943 9417943]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Interferons]]
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[[Category: Gsell, B.]]
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[[Category: Large Structures]]
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[[Category: Klaus, W.]]
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[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Labhardt, A M.]]
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[[Category: Gsell B]]
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[[Category: Senn, H.]]
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[[Category: Klaus W]]
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[[Category: Wipf, B.]]
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[[Category: Labhardt AM]]
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[[Category: Cytokine]]
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[[Category: Senn H]]
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[[Category: Interferon]]
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[[Category: Wipf B]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 13:58:08 2008''
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Current revision

INTERFERON ALPHA-2A, NMR, 24 STRUCTURES

PDB ID 1itf

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