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1j79

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{{Seed}}
 
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[[Image:1j79.png|left|200px]]
 
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==Molecular Structure of Dihydroorotase: A Paradigm for Catalysis Through the Use of a Binuclear Metal Center==
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The line below this paragraph, containing "STRUCTURE_1j79", creates the "Structure Box" on the page.
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<StructureSection load='1j79' size='340' side='right'caption='[[1j79]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1j79]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J79 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J79 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene>, <scene name='pdbligand=NCD:N-CARBAMOYL-L-ASPARTATE'>NCD</scene>, <scene name='pdbligand=ORO:OROTIC+ACID'>ORO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_1j79| PDB=1j79 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j79 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j79 OCA], [https://pdbe.org/1j79 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j79 RCSB], [https://www.ebi.ac.uk/pdbsum/1j79 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j79 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PYRC_ECOLI PYRC_ECOLI]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j7/1j79_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1j79 ConSurf].
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<div style="clear:both"></div>
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===Molecular Structure of Dihydroorotase: A Paradigm for Catalysis Through the Use of a Binuclear Metal Center===
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==See Also==
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*[[Dihydroorotase 3D structures|Dihydroorotase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_11401542}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 11401542 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11401542}}
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==About this Structure==
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1J79 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J79 OCA].
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==Reference==
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Molecular structure of dihydroorotase: a paradigm for catalysis through the use of a binuclear metal center., Thoden JB, Phillips GN Jr, Neal TM, Raushel FM, Holden HM, Biochemistry. 2001 Jun 19;40(24):6989-97. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11401542 11401542]
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[[Category: Dihydroorotase]]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Holden, H M.]]
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[[Category: Holden HM]]
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[[Category: Jr., G N.Phillips.]]
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[[Category: Neal TM]]
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[[Category: Neal, T M.]]
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[[Category: Phillips Jr GN]]
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[[Category: Raushel, F M.]]
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[[Category: Raushel FM]]
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[[Category: Thoden, J B.]]
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[[Category: Thoden JB]]
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[[Category: Metalloenzyme]]
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[[Category: Pyrimidine biosynthesis]]
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[[Category: Tim barrel]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 14:34:34 2008''
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Current revision

Molecular Structure of Dihydroorotase: A Paradigm for Catalysis Through the Use of a Binuclear Metal Center

PDB ID 1j79

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