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1jer

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[[Image:1jer.gif|left|200px]]<br />
 
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<applet load="1jer" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1jer, resolution 1.6&Aring;" />
 
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'''CUCUMBER STELLACYANIN, CU2+, PH 7.0'''<br />
 
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==Overview==
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==CUCUMBER STELLACYANIN, CU2+, PH 7.0==
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Stellacyanins are blue (type I) copper glycoproteins that differ from, other members of the cupredoxin family in their spectroscopic and electron, transfer properties. Until now, stellacyanins have eluded structure, determination. Here we report the three-dimensional crystal structure of, the 109 amino acid, non-glycosylated copper binding domain of recombinant, cucumber stellacyanin refined to 1.6 A resolution. The crystallographic, R-value for all 18,488 reflections (sigma &gt; 0) between 50-1.6 A is 0.195., The overall fold is organized in two beta-sheets, both with four, beta-stands. Two alpha-helices are found in loop regions between, beta-strands. The beta-sheets form a beta-sandwich similar to those found, in other cupredoxins, but some features differ from proteins such as, ... [[http://ispc.weizmann.ac.il/pmbin/getpm?8931136 (full description)]]
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<StructureSection load='1jer' size='340' side='right'caption='[[1jer]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[1jer]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cucumis_sativus Cucumis sativus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JER OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JER FirstGlance]. <br>
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1JER is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Cucumis_sativus Cucumis sativus]] with CU as [[http://en.wikipedia.org/wiki/ligand ligand]]. Structure known Active Site: CU. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1JER OCA]].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jer FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jer OCA], [https://pdbe.org/1jer PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jer RCSB], [https://www.ebi.ac.uk/pdbsum/1jer PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jer ProSAT]</span></td></tr>
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A missing link in cupredoxins: crystal structure of cucumber stellacyanin at 1.6 A resolution., Hart PJ, Nersissian AM, Herrmann RG, Nalbandyan RM, Valentine JS, Eisenberg D, Protein Sci. 1996 Nov;5(11):2175-83. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8931136 8931136]
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CPC_CUCSA CPC_CUCSA]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/je/1jer_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jer ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Cucumis sativus]]
[[Category: Cucumis sativus]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Eisenberg, D.]]
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[[Category: Eisenberg D]]
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[[Category: Hart, P.J.]]
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[[Category: Hart PJ]]
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[[Category: Herrmann, R.G.]]
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[[Category: Herrmann RG]]
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[[Category: Nalbandyan, R.M.]]
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[[Category: Nalbandyan RM]]
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[[Category: Nersissian, A.M.]]
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[[Category: Nersissian AM]]
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[[Category: Valentine, J.S.]]
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[[Category: Valentine JS]]
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[[Category: CU]]
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[[Category: copper]]
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[[Category: electron transport]]
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[[Category: glycoprotein]]
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[[Category: hydroxylation]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 11:09:42 2007''
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Current revision

CUCUMBER STELLACYANIN, CU2+, PH 7.0

PDB ID 1jer

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