1jjh

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{{Seed}}
 
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[[Image:1jjh.png|left|200px]]
 
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==E2 DNA-binding Domain from Bovine Papillomavirus Type 1==
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The line below this paragraph, containing "STRUCTURE_1jjh", creates the "Structure Box" on the page.
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<StructureSection load='1jjh' size='340' side='right'caption='[[1jjh]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1jjh]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Deltapapillomavirus_4 Deltapapillomavirus 4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JJH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JJH FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jjh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jjh OCA], [https://pdbe.org/1jjh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jjh RCSB], [https://www.ebi.ac.uk/pdbsum/1jjh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jjh ProSAT]</span></td></tr>
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{{STRUCTURE_1jjh| PDB=1jjh | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/VE2_BPV1 VE2_BPV1] E2 regulates viral transcription and DNA replication. Binds to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory region. Can either activate or repress transcription depending on E2RE's position with regards to proximal promoter elements. Repression occurs by sterically hindering the assembly of the transcription initiation complex. The E1-E2 complex binds to the origin of DNA replication.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jj/1jjh_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jjh ConSurf].
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<div style="clear:both"></div>
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===E2 DNA-binding Domain from Bovine Papillomavirus Type 1===
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==See Also==
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*[[Regulatory protein E2|Regulatory protein E2]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_9500927}}, adds the Publication Abstract to the page
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[[Category: Deltapapillomavirus 4]]
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(as it appears on PubMed at http://www.pubmed.gov), where 9500927 is the PubMed ID number.
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[[Category: Large Structures]]
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[[Category: Hegde RS]]
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{{ABSTRACT_PUBMED_9500927}}
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[[Category: Kim SS]]
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[[Category: Schapira M]]
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==About this Structure==
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[[Category: Wang AF]]
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1JJH is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Bovine_papillomavirus_type_1 Bovine papillomavirus type 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JJH OCA].
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==Reference==
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<ref group="xtra">PMID:9500927</ref><references group="xtra"/>
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[[Category: Bovine papillomavirus type 1]]
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[[Category: Hegde, R S.]]
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[[Category: Kim, S S.]]
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[[Category: Schapira, M.]]
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[[Category: Wang, A F.]]
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[[Category: Bpv-1]]
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[[Category: Dna-binding domain]]
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[[Category: E2]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 05:32:46 2009''
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Current revision

E2 DNA-binding Domain from Bovine Papillomavirus Type 1

PDB ID 1jjh

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OCA

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