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1jpe

From Proteopedia

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{{Seed}}
 
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[[Image:1jpe.png|left|200px]]
 
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==Crystal structure of DsbD-alpha; the N-terminal domain of DsbD==
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The line below this paragraph, containing "STRUCTURE_1jpe", creates the "Structure Box" on the page.
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<StructureSection load='1jpe' size='340' side='right'caption='[[1jpe]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1jpe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JPE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JPE FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jpe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jpe OCA], [https://pdbe.org/1jpe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jpe RCSB], [https://www.ebi.ac.uk/pdbsum/1jpe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jpe ProSAT]</span></td></tr>
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{{STRUCTURE_1jpe| PDB=1jpe | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DSBD_ECOLI DSBD_ECOLI] Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm, thereby maintaining the active site of DsbC, DsbE and DsbG in a reduced state. This transfer involves a cascade of disulfide bond formation and reduction steps.[HAMAP-Rule:MF_00399]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jp/1jpe_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jpe ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of DsbD-alpha; the N-terminal domain of DsbD===
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==See Also==
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*[[Thiol:disulfide interchange protein 3D structures|Thiol:disulfide interchange protein 3D structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12234918}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 12234918 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12234918}}
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==About this Structure==
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1JPE is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JPE OCA].
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==Reference==
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The disulfide bond isomerase DsbC is activated by an immunoglobulin-fold thiol oxidoreductase: crystal structure of the DsbC-DsbDalpha complex., Haebel PW, Goldstone D, Katzen F, Beckwith J, Metcalf P, EMBO J. 2002 Sep 16;21(18):4774-84. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12234918 12234918]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Goldstone, D.]]
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[[Category: Goldstone D]]
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[[Category: Haebel, P W.]]
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[[Category: Haebel PW]]
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[[Category: Metcalf, P.]]
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[[Category: Metcalf P]]
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[[Category: Disulfide bond formation]]
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[[Category: Electron transport]]
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[[Category: Inner membrane]]
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[[Category: Redox-active center]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 20:35:41 2008''
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Current revision

Crystal structure of DsbD-alpha; the N-terminal domain of DsbD

PDB ID 1jpe

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