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1jvk

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{{Seed}}
 
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[[Image:1jvk.png|left|200px]]
 
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==THREE-DIMENSIONAL STRUCTURE OF AN IMMUNOGLOBULIN LIGHT CHAIN DIMER ACTING AS A LETHAL AMYLOID PRECURSOR==
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The line below this paragraph, containing "STRUCTURE_1jvk", creates the "Structure Box" on the page.
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<StructureSection load='1jvk' size='340' side='right'caption='[[1jvk]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1jvk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JVK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JVK FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.94&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
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{{STRUCTURE_1jvk| PDB=1jvk | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jvk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jvk OCA], [https://pdbe.org/1jvk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jvk RCSB], [https://www.ebi.ac.uk/pdbsum/1jvk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jvk ProSAT]</span></td></tr>
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</table>
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===THREE-DIMENSIONAL STRUCTURE OF AN IMMUNOGLOBULIN LIGHT CHAIN DIMER ACTING AS A LETHAL AMYLOID PRECURSOR===
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== Function ==
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[https://www.uniprot.org/uniprot/Q6PJG0_HUMAN Q6PJG0_HUMAN]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_11976493}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 11976493 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jv/1jvk_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_11976493}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JVK OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jvk ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Three-dimensional structure of an immunoglobulin light-chain dimer with amyloidogenic properties., Bourne PC, Ramsland PA, Shan L, Fan ZC, DeWitt CR, Shultz BB, Terzyan SS, Moomaw CR, Slaughter CA, Guddat LW, Edmundson AB, Acta Crystallogr D Biol Crystallogr. 2002 May;58(Pt 5):815-23. Epub 2002, Apr 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11976493 11976493]
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</StructureSection>
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[[Category: Bourne, P C.]]
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[[Category: Homo sapiens]]
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[[Category: DeWitt, C R.]]
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[[Category: Large Structures]]
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[[Category: Edmundson, A B.]]
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[[Category: Bourne PC]]
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[[Category: Fan, Z C.]]
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[[Category: DeWitt CR]]
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[[Category: Ramsland, P A.]]
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[[Category: Edmundson AB]]
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[[Category: Shan, L.]]
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[[Category: Fan Z-C]]
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[[Category: Shultz, B B.]]
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[[Category: Ramsland PA]]
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[[Category: Terzyan, S S.]]
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[[Category: Shan L]]
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[[Category: Amyloidogenic]]
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[[Category: Shultz BB]]
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[[Category: Immunoglobulin light chain dimer]]
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[[Category: Terzyan SS]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 21:00:06 2008''
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Current revision

THREE-DIMENSIONAL STRUCTURE OF AN IMMUNOGLOBULIN LIGHT CHAIN DIMER ACTING AS A LETHAL AMYLOID PRECURSOR

PDB ID 1jvk

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