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1kbe

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{{Seed}}
 
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[[Image:1kbe.png|left|200px]]
 
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<!--
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==Solution structure of the cysteine-rich C1 domain of Kinase Suppressor of Ras==
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The line below this paragraph, containing "STRUCTURE_1kbe", creates the "Structure Box" on the page.
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<StructureSection load='1kbe' size='340' side='right'caption='[[1kbe]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1kbe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KBE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KBE FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_1kbe| PDB=1kbe | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kbe OCA], [https://pdbe.org/1kbe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kbe RCSB], [https://www.ebi.ac.uk/pdbsum/1kbe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kbe ProSAT]</span></td></tr>
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</table>
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===Solution structure of the cysteine-rich C1 domain of Kinase Suppressor of Ras===
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== Function ==
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[https://www.uniprot.org/uniprot/KSR1_MOUSE KSR1_MOUSE] Location-regulated scaffolding protein connecting MEK to RAF. Promotes MEK and RAF phosphorylation and activity through assembly of an activated signaling complex. By itself, it has no demonstrated kinase activity.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_11786023}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 11786023 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kb/1kbe_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_11786023}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1KBE is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KBE OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kbe ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Solution structure and functional analysis of the cysteine-rich C1 domain of kinase suppressor of Ras (KSR)., Zhou M, Horita DA, Waugh DS, Byrd RA, Morrison DK, J Mol Biol. 2002 Jan 18;315(3):435-46. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11786023 11786023]
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Single protein]]
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[[Category: Byrd RA]]
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[[Category: Byrd, R A.]]
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[[Category: Horita DA]]
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[[Category: Horita, D A.]]
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[[Category: Morrison DK]]
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[[Category: Morrison, D K.]]
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[[Category: Waugh DS]]
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[[Category: Waugh, D S.]]
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[[Category: Zhou M]]
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[[Category: Zhou, M.]]
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[[Category: Cysteine-rich domain]]
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[[Category: Kinase suppressor of ra]]
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[[Category: Ksr]]
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[[Category: Zinc-binding protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 10:04:53 2008''
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Current revision

Solution structure of the cysteine-rich C1 domain of Kinase Suppressor of Ras

PDB ID 1kbe

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