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1kt2

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[[Image:1kt2.png|left|200px]]
 
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{{STRUCTURE_1kt2| PDB=1kt2 | SCENE= }}
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==CRYSTAL STRUCTURE OF CLASS II MHC MOLECULE IEK BOUND TO MOTH CYTOCHROME C PEPTIDE==
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<StructureSection load='1kt2' size='340' side='right'caption='[[1kt2]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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===CRYSTAL STRUCTURE OF CLASS II MHC MOLECULE IEK BOUND TO MOTH CYTOCHROME C PEPTIDE===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1kt2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Lonomia_obliqua Lonomia obliqua] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KT2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KT2 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_11956295}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kt2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kt2 OCA], [https://pdbe.org/1kt2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kt2 RCSB], [https://www.ebi.ac.uk/pdbsum/1kt2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kt2 ProSAT]</span></td></tr>
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[[1kt2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KT2 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HA21_MOUSE HA21_MOUSE]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kt/1kt2_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kt2 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Major histocompatibility complex|Major histocompatibility complex]]
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*[[MHC 3D structures|MHC 3D structures]]
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*[[MHC II 3D structures|MHC II 3D structures]]
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==Reference==
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__TOC__
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<ref group="xtra">PMID:011956295</ref><references group="xtra"/>
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Lonomia obliqua]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Chiang, H.]]
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[[Category: Chiang H]]
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[[Category: Crawford, F.]]
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[[Category: Crawford F]]
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[[Category: Dai, S.]]
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[[Category: Dai S]]
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[[Category: Fremont, D H.]]
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[[Category: Fremont DH]]
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[[Category: Kappler, J.]]
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[[Category: Kappler J]]
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[[Category: Marrack, P.]]
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[[Category: Marrack P]]
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[[Category: Antigen presentation]]
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[[Category: Cytochrome]]
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[[Category: Immune system]]
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[[Category: Protein-peptide complex]]
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[[Category: T cell receptor]]
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Current revision

CRYSTAL STRUCTURE OF CLASS II MHC MOLECULE IEK BOUND TO MOTH CYTOCHROME C PEPTIDE

PDB ID 1kt2

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