This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1kwm

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "1kwm" [edit=sysop:move=sysop])
Current revision (08:04, 3 April 2024) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1kwm.png|left|200px]]
 
-
{{STRUCTURE_1kwm| PDB=1kwm | SCENE= }}
+
==Human procarboxypeptidase B: Three-dimensional structure and implications for thrombin-activatable fibrinolysis inhibitor (TAFI)==
-
 
+
<StructureSection load='1kwm' size='340' side='right'caption='[[1kwm]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
-
===Human procarboxypeptidase B: Three-dimensional structure and implications for thrombin-activatable fibrinolysis inhibitor (TAFI)===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[1kwm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KWM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KWM FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_12162965}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kwm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kwm OCA], [https://pdbe.org/1kwm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kwm RCSB], [https://www.ebi.ac.uk/pdbsum/1kwm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kwm ProSAT]</span></td></tr>
-
[[1kwm]] is a 2 chain structure of [[Carboxypeptidase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KWM OCA].
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/CBPB1_HUMAN CBPB1_HUMAN]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kw/1kwm_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kwm ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
-
*[[Carboxypeptidase|Carboxypeptidase]]
+
*[[Carboxypeptidase 3D structures|Carboxypeptidase 3D structures]]
-
 
+
__TOC__
-
==Reference==
+
</StructureSection>
-
<ref group="xtra">PMID:012162965</ref><references group="xtra"/>
+
-
[[Category: Carboxypeptidase B]]
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Aviles, F X.]]
+
[[Category: Large Structures]]
-
[[Category: Coll, M.]]
+
[[Category: Aviles F-X]]
-
[[Category: Ferrer-Orta, C.]]
+
[[Category: Coll M]]
-
[[Category: Gomis-Rueth, F X.]]
+
[[Category: Ferrer-Orta C]]
-
[[Category: Pereira, P J.B.]]
+
[[Category: Gomis-Rueth F-X]]
-
[[Category: Segura-Martin, S.]]
+
[[Category: Pereira PJB]]
-
[[Category: Vendrell, J.]]
+
[[Category: Segura-Martin S]]
-
[[Category: Hydrolase]]
+
[[Category: Vendrell J]]
-
[[Category: Procarboxypeptidase b]]
+

Current revision

Human procarboxypeptidase B: Three-dimensional structure and implications for thrombin-activatable fibrinolysis inhibitor (TAFI)

PDB ID 1kwm

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools