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1l7v

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[[Image:1l7v.png|left|200px]]
 
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{{STRUCTURE_1l7v| PDB=1l7v | SCENE= }}
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==Bacterial ABC Transporter Involved in B12 Uptake==
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<StructureSection load='1l7v' size='340' side='right'caption='[[1l7v]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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===Bacterial ABC Transporter Involved in B12 Uptake===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1l7v]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L7V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L7V FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12004122}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=V4O:CYCLO-TETRAMETAVANADATE'>V4O</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l7v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l7v OCA], [https://pdbe.org/1l7v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l7v RCSB], [https://www.ebi.ac.uk/pdbsum/1l7v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l7v ProSAT]</span></td></tr>
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[[1l7v]] is a 4 chain structure of [[ABC transporter]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L7V OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BTUC_ECOLI BTUC_ECOLI] Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane.[HAMAP-Rule:MF_01004]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l7/1l7v_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1l7v ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[ABC transporter|ABC transporter]]
*[[ABC transporter|ABC transporter]]
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*[[ABC transporter 3D structures|ABC transporter 3D structures]]
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==Reference==
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__TOC__
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<ref group="xtra">PMID:012004122</ref><ref group="xtra">PMID:012667056</ref><references group="xtra"/>
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Vitamin B12-transporting ATPase]]
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[[Category: Large Structures]]
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[[Category: Lee, A T.]]
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[[Category: Lee AT]]
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[[Category: Locher, K P.]]
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[[Category: Locher KP]]
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[[Category: Rees, D C.]]
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[[Category: Rees DC]]
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[[Category: Abc transporter]]
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[[Category: Atp binding cassette]]
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[[Category: Atp hydrolysis]]
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[[Category: Integral membrane protein]]
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[[Category: Transport protein-hydrolase complex]]
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[[Category: Vitamin b12]]
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Current revision

Bacterial ABC Transporter Involved in B12 Uptake

PDB ID 1l7v

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