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1lbe
From Proteopedia
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| - | [[Image:1lbe.gif|left|200px]]<br /><applet load="1lbe" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1lbe, resolution 2.4Å" /> | ||
| - | '''APLYSIA ADP RIBOSYL CYCLASE'''<br /> | ||
| - | == | + | ==APLYSIA ADP RIBOSYL CYCLASE== |
| - | + | <StructureSection load='1lbe' size='340' side='right'caption='[[1lbe]], [[Resolution|resolution]] 2.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[1lbe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aplysia_californica Aplysia californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LBE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LBE FirstGlance]. <br> |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lbe OCA], [https://pdbe.org/1lbe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lbe RCSB], [https://www.ebi.ac.uk/pdbsum/1lbe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lbe ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | + | == Function == | |
| + | [https://www.uniprot.org/uniprot/NADA_APLCA NADA_APLCA] Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for calcium mobilization from endoplasmic reticulum. Also has cADPr hydrolase activity.<ref>PMID:11829748</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lb/1lbe_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lbe ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Aplysia californica]] | [[Category: Aplysia californica]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | + | [[Category: Lee HC]] | |
| - | [[Category: Lee | + | [[Category: Levitt DG]] |
| - | [[Category: Levitt | + | [[Category: Mcree DE]] |
| - | [[Category: Mcree | + | [[Category: Prasad GS]] |
| - | [[Category: Prasad | + | [[Category: Stout CD]] |
| - | [[Category: Stout | + | [[Category: Stura EA]] |
| - | [[Category: Stura | + | |
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Current revision
APLYSIA ADP RIBOSYL CYCLASE
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