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Virus protease 3D structures
From Proteopedia
(Difference between revisions)
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**[[5gjb]], [[5mfx]] – NS3 + RNA <br /> | **[[5gjb]], [[5mfx]] – NS3 + RNA <br /> | ||
**[[5rhg]], [[5rhh]], [[5rhi]], [[5rhj]], [[5rhk]], [[5rhl]], [[5rhm]], [[5rho]], [[5rhp]], [[5rhq]], [[5rhr]], [[5rhs]], [[5rht]], [[5rhu]], [[5rhv]], [[5rhw]], [[5rhx]], [[5rhy]]– NS3 + inhibitor<br /> | **[[5rhg]], [[5rhh]], [[5rhi]], [[5rhj]], [[5rhk]], [[5rhl]], [[5rhm]], [[5rho]], [[5rhp]], [[5rhq]], [[5rhr]], [[5rhs]], [[5rht]], [[5rhu]], [[5rhv]], [[5rhw]], [[5rhx]], [[5rhy]]– NS3 + inhibitor<br /> | ||
| - | **[[5gjc]], [[5gpi]], [5h4i]], [[5h6v]], [[5lc0]], [[5yod]], [[5yof]], [[5zmq]], [[5zms]], [[5zob]], [[6jpw]], [[6kk2]], [[6kk3]], [[6kk4]], [[6kk5]], [[6kk6]], [[6kpq]], [[6l4z]], [[6l50]], [[6y3b]] – NS2B + NS3 + inhibitor<br /> | + | **[[5gjc]], [[5gpi]], [[5h4i]], [[5h6v]], [[5lc0]], [[5yod]], [[5yof]], [[5zmq]], [[5zms]], [[5zob]], [[6jpw]], [[6kk2]], [[6kk3]], [[6kk4]], [[6kk5]], [[6kk6]], [[6kpq]], [[6l4z]], [[6l50]], [[6y3b]] – NS2B + NS3 + inhibitor<br /> |
*'''Pseudorabies virus protease''' | *'''Pseudorabies virus protease''' | ||
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**[[3sj9]] – CSVP 3C (mutant) + peptide inhibitor <br /> | **[[3sj9]] – CSVP 3C (mutant) + peptide inhibitor <br /> | ||
| - | *'''Human poliovirus protease''' | + | *'''Human poliovirus 3C protease''' |
**[[1l1n]] – HPV <br /> | **[[1l1n]] – HPV <br /> | ||
**[[2ijd]] – HPV (mutant) <br /> | **[[2ijd]] – HPV (mutant) <br /> | ||
| + | **[[4dcd]] – HPV + peptide inhibitor <br /> | ||
*'''Human rhinovirus protease''' | *'''Human rhinovirus protease''' | ||
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**[[5x45]] – HRVP 2A – human rhinovirus C15 <br /> | **[[5x45]] – HRVP 2A – human rhinovirus C15 <br /> | ||
| - | *'''Human enterovirus protease''' | + | *'''Human enterovirus protease A71''' |
| - | **[[3osy]], [[4ghq]] – HEVP | + | **[[3osy]], [[4ghq]], [[8cny]] – HEVP <br /> |
**[[3r0f]] – HEVP (mutant) <br /> | **[[3r0f]] – HEVP (mutant) <br /> | ||
**[[3sjk]] – HEVP (mutant) + peptide inhibitor <br /> | **[[3sjk]] – HEVP (mutant) + peptide inhibitor <br /> | ||
| - | **[[4ght]], [[5bpe]], [[5c1u]], [[5c1x]], [[5c1y]], [[5c20]], [[5dp3]], [[5dp4]], [[5dp5]], [[5dp6]], [[5dp7]], [[5dp8]], [[5dp9]], [[5dpa]], [[5gsw]], [[5hxf]], [[5wq2]], [[6lka]] – HEVP + inhibitor <br /> | + | **[[4ght]], [[5bpe]], [[5c1u]], [[5c1x]], [[5c1y]], [[5c20]], [[5dp3]], [[5dp4]], [[5dp5]], [[5dp6]], [[5dp7]], [[5dp8]], [[5dp9]], [[5dpa]], [[5gso]], [[5gsw]], [[5hxf]], [[5wq2]], [[6lka]], [[7dnc]] – HEVP + inhibitor <br /> |
**[[3sjo]], [[5hxf]], [[5wq2]] – HEVP + drug <br /> | **[[3sjo]], [[5hxf]], [[5wq2]] – HEVP + drug <br /> | ||
**[[3qzq]], [[3qzr]], [[3r0f]] – HEVP (mutant) + drug <br /> | **[[3qzq]], [[3qzr]], [[3r0f]] – HEVP (mutant) + drug <br /> | ||
| - | **[[3q3x]] – HEVP (mutant) | + | |
| + | *'''Human enterovirus protease B''' | ||
| + | |||
| + | **[[3q3x]] – HEVP (mutant) <br /> | ||
**[[3q3y]] – HEVP (mutant) + inhibitor <br /> | **[[3q3y]] – HEVP (mutant) + inhibitor <br /> | ||
**[[3ruo]] – HEVP + drug <br /> | **[[3ruo]] – HEVP + drug <br /> | ||
| - | **[[3zv8]] – HEVP residues 1549-1731 | + | |
| - | **[[3zv9]], [[3zva]], [[3zvb]], [[3zvc]], [[3zvd]], [[3zve]], [[3zvf]], [[3zvg]] – HEVP + inhibitor <br /> | + | *'''Human enterovirus protease D68''' |
| + | |||
| + | **[[3zv8]], [[8cnx]] – HEVP residues 1549-1731 <br /> | ||
| + | **[[8fl5]] – HEVP (mutant) <br /> | ||
| + | **[[3zv9]], [[3zva]], [[3zvb]], [[3zvc]], [[3zvd]], [[3zve]], [[3zvf]], [[3zvg]], [[7gnv]], [[7gnw]], [[7gnx]], [[7gny]], [[7gnz]], [[7go0]], [[7go1]], [[7go2]], [[7go3]], [[7go4]], [[7go5]], [[7go6]], [[7go7]], [[7go8]], [[7go9]], [[7goa]], [[7gob]], [[7goc]], [[7god]], [[7goe]], [[7gof]], [[7gog]], [[7goh]], [[7goi]], [[7goj]], [[7gok]], [[7gol]], [[7gom]], [[7gon]], [[7goo]], [[7gop]], [[7goq]], [[7gor]], [[7got]], [[7gou]], [[7gov]], [[7gow]], [[7gox]], [[7goy]], [[7goz]], [[7gp0]], [[7gp1]], [[7gp2]], [[7gp3]], [[7gp4]], [[7gp5]], [[7gp6]], [[7gp7]], [[7gp8]], [[7gp9]], [[7gpa]], [[7gpc]], [[7gpd]], [[7gpe]], [[7gpf]], [[7gpg]], [[7gph]], [[7gpi]], [[7gpj]], [[7gpl]], [[7gpm]], [[7gpn]], [[7gpo]], [[7gpp]], [[7gpq]], [[7gpr]], [[7gps]], [[7gpt]], [[7gpu]], [[7gpv]], [[7gpw]], [[7gpx]], [[7gpy]], [[7gpz]], [[7gq0]], [[7gq1]], [[7gq2]], [[7gq3]], [[7gq4]], [[7gq6]], [[7gq7]], [[7gq8]], [[7gq9]], [[7gqa]], [[7gqb]], [[7gqc]], [[7gqd]], [[7gqe]], [[7gqf]], [[7gqh]], [[7gqi]], [[7gqj]], [[7gqk]], [[7gql]], [[7gqm]], [[7gqn]], [[7gqo]], [[7gqp]], [[7gqq]], [[7gqr]] – HEVP + inhibitor <br /> | ||
| + | **[[7l8h]] – HEVP + drug <br /> | ||
*'''Porcine epidemic diarrhea virus protease''' | *'''Porcine epidemic diarrhea virus protease''' | ||
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**[[6ljb]], [[6lj9]] – ASFV – African swine fever virus<br /> | **[[6ljb]], [[6lj9]] – ASFV – African swine fever virus<br /> | ||
| + | |||
| + | *'''Senecavirus 3C protease residues 1509-1719''' | ||
| + | |||
| + | **[[6l0t]] – 3CP<br /> | ||
| + | |||
| + | *'''Norovirus 3C-like protease residues 1-173''' | ||
| + | |||
| + | **[[1wqs]] – 3CLP<br /> | ||
*'''Norovirus 3C-like protease residues 1101-1281''' | *'''Norovirus 3C-like protease residues 1101-1281''' | ||
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*'''SARS human corona virus 3C-like protease C-terminal 3241-3546''' | *'''SARS human corona virus 3C-like protease C-terminal 3241-3546''' | ||
| - | **[[1q2w]], [[1uj1]], [[1uk2]], [[1uk3]], [[1z1i]], [[2a5a]], [[2bx3]], [[2c3s]], [[2bx3]], [[2bx4]], [[2duc]], [[2gt7]], [[5r8t]], [[6m2q]], [[6wqf]], [[6xb0]], [[6xb1]], [[6xb2]], [[6xhu]], [[7bro]], [[7jp1]], [[7jpy]], [[7jun]], [[7k3t]], [[7kfi]], [[7lfp]], [[7khp]] – 3CLP – SARS-COV<br /> | + | **[[1q2w]], [[1uj1]], [[1uk2]], [[1uk3]], [[1z1i]], [[2a5a]], [[2bx3]], [[2c3s]], [[2bx3]], [[2bx4]], [[2duc]], [[2gt7]], [[3ebn]], [[3vb3]], [[5r8t]], [[6m2q]], [[6wqf]], [[6xb0]], [[6xb1]], [[6xb2]], [[6xhu]], [[6y2e]], [[7ar5]], [[7ar6]], [[7bro]], [[7dqz]], [[7jp1]], [[7jpy]], [[7jun]], [[7k3t]], [[7kfi]], [[7lfp]], [[7khp]] – 3CLP – SARS-COV<br /> |
| - | **[[1z1j]], [[2gt8]], [[2pwx]], [[2q6g]], [[2qc2]], [[2qcy]], [[3m3s]], [[3m3t]], [[3m3v]], [[3fzd]], [[3f9e]], [[3f9f]], [[3f9g]], [[3f9h]], [[3ea7]], [[3ea8]], [[3ea9]], [[3eaj]], [[3e91]], [[3ee7]], [[3aw1]], [[4hi3]], [[5b6o]], [[7joy]], [[ | + | **[[1z1j]], [[2gt8]], [[2pwx]], [[2q6g]], [[2qc2]], [[2qcy]], [[3m3s]], [[3m3t]], [[3m3v]], [[3fzd]], [[3f9e]], [[3f9f]], [[3f9g]], [[3f9h]], [[3ea7]], [[3ea8]], [[3ea9]], [[3eaj]], [[3e91]], [[3ee7]], [[3aw1]], [[4hi3]], [[5b6o]], [[7joy]], [[7n6n]], [[7t2v]] – 3CLP (mutant) – SARS-COV<br /> |
**[[2liz]] – 3CLP – SARS-COV - NMR<br /> | **[[2liz]] – 3CLP – SARS-COV - NMR<br /> | ||
| - | **[[3ebn]] – 3CLP C-terminal 3429-3546<br /> | ||
**[[6wtj]], [[6wtk]], [[6wtm]], [[6xqs]], [[6xqt]], [[6xqu]], [[7aol]], [[7b83]], [[7brp]], [[7buy]], [[7c6s]], [[7jyc]], [[7k6d]], [[7k6e]] – 3CLP + drug – hCOV-2<br /> | **[[6wtj]], [[6wtk]], [[6wtm]], [[6xqs]], [[6xqt]], [[6xqu]], [[7aol]], [[7b83]], [[7brp]], [[7buy]], [[7c6s]], [[7jyc]], [[7k6d]], [[7k6e]] – 3CLP + drug – hCOV-2<br /> | ||
**[[3d23]] – 3CLP + inhibitor – hCOV-HKU1<br /> | **[[3d23]] – 3CLP + inhibitor – hCOV-HKU1<br /> | ||
| - | **[[ | + | **[[3tlo]], [[7e6l]], [[7e6m]], [[7e6n]], [[7e6r]] – NL633CLP 2940-3242 – hCOV-NL63<br /> |
| - | **[[1wof]], [[2amd]], [[2amq]], [[2amp]], [[2gx4]], [[2gz7]], [[2gz8]], [[2op9]], [[2ops]], [[2vj1]], [[2ynb]], [[3atw]], [[3avz]], [[3d62]], [[3iwm]], [[3sn8]], [[3v3m]], [[4tww]], [[4twy]], [[4wy3]], [[5re4]], [[5re5]], [[5re6]], [[5re7]], [[5re8]], [[5re9]], [[5rea]], [[5reb]], [[5rec]], [[5red]], [[5ree]], [[5ref]], [[5reg]], [[5rep]], [[5rer]], [[5res]], [[5ret]], [[5reu]], [[5rew]], [[5rex]], [[5rey]], [[5rez]], [[5rf1]], [[5rf2]], [[5rf3]], [[5rf4]], [[5rf5]], [[5rf6]], [[5rf9]], [[5rfa]], [[5rfb]], [[5rfc]], [[5rfd]], [[5rfe]], [[5rff]], [[5rfg]], [[5rfh]], [[5rg1]], [[5rg2]], [[5rg3]], [[5rgg]], [[5rgh]], [[5rgi]], [[5rgj]], [[5rgk]], [[5rgl]], [[5rgm]], [[5rgn]], [[5rgo]], [[5rgp]], [[5rgq]], [[5rgr]], [[5rgs]], [[6lu7]], [[6lze]], [[6m0k]], [[6m2n]], [[6w2a]], [[6w63]], [[6w79]], [[6wco]], [[6xhl]], [[6xhm]], [[6xhn]], [[6xho]], [[6xmk]], [[7bqy]], [[7c6u]], [[7d1m]], [[7jkv]], [[7jpz]], [[7jq0]], [[7jq1]], [[7jq2]], [[7jq3]], [[7jq4]], [[7jq5]], [[7ldx]] – 3CLP + inhibitor – SARS-COV<br /> | + | **[[5gwy]], [[7eov]] – NL633CLP + inhibitor <br /> |
| - | **[[5c5n]], [[5c5o]] – 3CLP (mutant) + inhibitor – SARS-COV<br /> | + | **[[1wof]], [[2amd]], [[2amq]], [[2amp]], [[2gx4]], [[2gz7]], [[2gz8]], [[2op9]], [[2ops]], [[2vj1]], [[2ynb]], [[2z94]], [[3atw]], [[3avz]], [[3d62]], [[3iwm]], [[3sn8]], [[3v3m]], [[4tww]], [[4twy]], [[4wy3]], [[5re4]], [[5re5]], [[5re6]], [[5re7]], [[5re8]], [[5re9]], [[5rea]], [[5reb]], [[5rec]], [[5red]], [[5ree]], [[5ref]], [[5reg]], [[5rep]], [[5rer]], [[5res]], [[5ret]], [[5reu]], [[5rew]], [[5rex]], [[5rey]], [[5rez]], [[5rf1]], [[5rf2]], [[5rf3]], [[5rf4]], [[5rf5]], [[5rf6]], [[5rf9]], [[5rfa]], [[5rfb]], [[5rfc]], [[5rfd]], [[5rfe]], [[5rff]], [[5rfg]], [[5rfh]], [[5rg1]], [[5rg2]], [[5rg3]], [[5rgg]], [[5rgh]], [[5rgi]], [[5rgj]], [[5rgk]], [[5rgl]], [[5rgm]], [[5rgn]], [[5rgo]], [[5rgp]], [[5rgq]], [[5rgr]], [[5rgs]], [[6lnq]], [[6lny]], [[6lo0]], [[6lu7]], [[6lze]], [[6m0k]], [[6m2n]], [[6w2a]], [[6w63]], [[6w79]], [[6wco]], [[6xhl]], [[6xhm]], [[6xhn]], [[6xho]], [[6xmk]], [[7a1u]], [[7aga]], [[7aha]], [[7amj]], [[7bqy]], [[7c6u]], [[7d1m]], [[7jkv]], [[7jpz]], [[7jq0]], [[7jq1]], [[7jq2]], [[7jq3]], [[7jq4]], [[7jq5]], [[7k0e]], [[7k0f]], [[7k0g]], [[7k0h]], [[7ldx]], [[7vic]], [[7xar]], [[8uld]] – 3CLP + inhibitor – SARS-COV<br /> |
| + | **[[5c5n]], [[5c5o]], [[8h6i]] – 3CLP (mutant) + inhibitor – SARS-COV<br /> | ||
**[[2vj1]], [[3tit]], [[3tiu]] – 3CLP + unsaturated ester<br /> | **[[2vj1]], [[3tit]], [[3tiu]] – 3CLP + unsaturated ester<br /> | ||
| - | **[[2zu2]], [[2zu4]], [[2zu5]], [[3tns]], [[3tnt]], [[ | + | **[[2zu2]], [[2zu4]], [[2zu5]], [[3aw0]], [[3tns]], [[3tnt]], [[3vb4]], [[3vb5]], [[3vb6]], [[3vb7]], [[7t2u]] – 3CLP + peptidomimetic compound<br /> |
**[[2z9g]] – 3CLP + benzene + Hg<br /> | **[[2z9g]] – 3CLP + benzene + Hg<br /> | ||
**[[2z9j]], [[2z9k]], [[2z9l]] – 3CLP + Zn compound<br /> | **[[2z9j]], [[2z9k]], [[2z9l]] – 3CLP + Zn compound<br /> | ||
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**[[5tl6]], [[5tl7]], [[6xa9]], [[6xaa]], [[6yva]] – PLpro (mutant) + mISG15<br /> | **[[5tl6]], [[5tl7]], [[6xa9]], [[6xaa]], [[6yva]] – PLpro (mutant) + mISG15<br /> | ||
**[[3e9s]], [[3mj5]], [[7cjm]], [[7cmd]] – PLpro + inhibitor<br /> | **[[3e9s]], [[3mj5]], [[7cjm]], [[7cmd]] – PLpro + inhibitor<br /> | ||
| - | **[[ | + | **[[7e35]], [[7jrn]] – PLpro (mutant) + inhibitor<br /> |
**[[6wuu]], [[6wx4]] – PLpro + peptide inhibitor<br /> | **[[6wuu]], [[6wx4]] – PLpro + peptide inhibitor<br /> | ||
**[[4mm3]], [[5e6j]] – PLpro + ubiquitin<br /> | **[[4mm3]], [[5e6j]] – PLpro + ubiquitin<br /> | ||
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**[[5c3n]], [[5ko3]] – ORF1A<br /> | **[[5c3n]], [[5ko3]] – ORF1A<br /> | ||
| - | **[[4wmd]], [[4wme]], [[4wmf]] – ORF1A (mutant)<br /> | + | **[[4wmd]], [[4wme]], [[4wmf]], [[8e7t]] – ORF1A (mutant)<br /> |
**[[4ylu]], [[5wkj]], [[5wkk]], [[5wkl]], [[5wkm]], [[6vgy]], [[6vgz]], [[6vh0]], [[6vh1]], [[6vh2]], [[6vh3]] – ORF1A + inhibitor<br /> | **[[4ylu]], [[5wkj]], [[5wkk]], [[5wkl]], [[5wkm]], [[6vgy]], [[6vgz]], [[6vh0]], [[6vh1]], [[6vh2]], [[6vh3]] – ORF1A + inhibitor<br /> | ||
| - | **[[4rsp]] – ORF1A + peptide inhibitor<br /> | + | **[[4rsp]], [[7d3c]] – ORF1A + peptide inhibitor<br /> |
**[[5zu7]], [[5zu9]], [[5zua]] – ORF1A + nucleotide<br /> | **[[5zu7]], [[5zu9]], [[5zua]] – ORF1A + nucleotide<br /> | ||
**[[5zub]] – ORF1A + NAD<br /> | **[[5zub]] – ORF1A + NAD<br /> | ||
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**[[4wur]] – ORF1AB (mutant) + ubiquitin <br /> | **[[4wur]] – ORF1AB (mutant) + ubiquitin <br /> | ||
| + | *'''Mason-pfizer monkey virus protease ''' | ||
| + | |||
| + | **[[7bgt]], [[7bgu]] – MPMVP + inhibitor <br /> | ||
| + | *'''Maize rayado fino virus protease ''' | ||
| + | **[[7mia]] – MRFVP + inhibitor <br /> | ||
| + | **[[7mic]] – MRFVP + ubiquitin<br /> | ||
}} | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Current revision
Updated on 03-April-2024 - For a general description of the protein see Virus protease
