This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
8rcw
From Proteopedia
(Difference between revisions)
| (3 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the Mycobacterium tuberculosis regulator VirS (N-terminal fragment 4-208) in complex with the lead compound SMARt751== | |
| - | + | <StructureSection load='8rcw' size='340' side='right'caption='[[8rcw]], [[Resolution|resolution]] 1.69Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8rcw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8RCW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8RCW FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.692Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=YQF:4,4,4-tris(fluoranyl)-1-[4-(4-fluorophenyl)piperidin-1-yl]butan-1-one'>YQF</scene></td></tr> |
| - | [[Category: Baulard | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8rcw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8rcw OCA], [https://pdbe.org/8rcw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8rcw RCSB], [https://www.ebi.ac.uk/pdbsum/8rcw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8rcw ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/VIRS_MYCTU VIRS_MYCTU] Regulates the expression of the mymA operon (Rv3083-Rv3089).<ref>PMID:14568148</ref> |
| - | [[Category: Tanina | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: Wintjens | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
| + | [[Category: Baulard AR]] | ||
| + | [[Category: Grosse C]] | ||
| + | [[Category: Megalizzi V]] | ||
| + | [[Category: Sigoillot M]] | ||
| + | [[Category: Tanina A]] | ||
| + | [[Category: Willand N]] | ||
| + | [[Category: Wintjens R]] | ||
Current revision
Crystal structure of the Mycobacterium tuberculosis regulator VirS (N-terminal fragment 4-208) in complex with the lead compound SMARt751
| |||||||||||
