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1it9

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{{Seed}}
 
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[[Image:1it9.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF AN ANTIGEN-BINDING FRAGMENT FROM A HUMANIZED VERSION OF THE ANTI-HUMAN FAS ANTIBODY HFE7A==
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The line below this paragraph, containing "STRUCTURE_1it9", creates the "Structure Box" on the page.
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<StructureSection load='1it9' size='340' side='right'caption='[[1it9]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1it9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IT9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IT9 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1it9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1it9 OCA], [https://pdbe.org/1it9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1it9 RCSB], [https://www.ebi.ac.uk/pdbsum/1it9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1it9 ProSAT]</span></td></tr>
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{{STRUCTURE_1it9| PDB=1it9 | SCENE= }}
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</table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/it/1it9_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1it9 ConSurf].
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<div style="clear:both"></div>
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===CRYSTAL STRUCTURE OF AN ANTIGEN-BINDING FRAGMENT FROM A HUMANIZED VERSION OF THE ANTI-HUMAN FAS ANTIBODY HFE7A===
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==See Also==
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*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12499636}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 12499636 is the PubMed ID number.
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[[Category: Mus musculus]]
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[[Category: Hanzawa H]]
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{{ABSTRACT_PUBMED_12499636}}
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[[Category: Haruyama H]]
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[[Category: Hata T]]
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==About this Structure==
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[[Category: Ito S]]
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IT9 OCA].
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[[Category: Miyadai K]]
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[[Category: Serizawa N]]
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==Reference==
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[[Category: Takahashi T]]
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Humanization of the mouse anti-Fas antibody HFE7A and crystal structure of the humanized HFE7A Fab fragment., Haruyama H, Ito S, Miyadai K, Takahashi T, Kawaida R, Takayama T, Hanzawa H, Hata T, Yamaguchi J, Yoshida-Kato H, Ichikawa K, Ohsumi J, Yonehara S, Serizawa N, Biol Pharm Bull. 2002 Dec;25(12):1537-45. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12499636 12499636]
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[[Category: Takayama T]]
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[[Category: Hanzawa, H.]]
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[[Category: Haruyama, H.]]
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[[Category: Hata, T.]]
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[[Category: Ito, S.]]
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[[Category: Miyadai, K.]]
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[[Category: Serizawa, N.]]
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[[Category: Takahashi, T.]]
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[[Category: Takayama, T.]]
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[[Category: Agonistic_antibody]]
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[[Category: Anti_fa]]
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[[Category: Antibody_humanization]]
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[[Category: Apoptosis]]
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[[Category: Fab]]
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[[Category: Immunoglobulin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 13:57:46 2008''
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Current revision

CRYSTAL STRUCTURE OF AN ANTIGEN-BINDING FRAGMENT FROM A HUMANIZED VERSION OF THE ANTI-HUMAN FAS ANTIBODY HFE7A

PDB ID 1it9

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