This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1lt7

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "1lt7" [edit=sysop:move=sysop])
Current revision (08:27, 10 April 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1lt7.png|left|200px]]
 
-
{{STRUCTURE_1lt7| PDB=1lt7 | SCENE= }}
+
==Oxidized Homo sapiens betaine-homocysteine S-methyltransferase in complex with four Sm(III) ions==
-
 
+
<StructureSection load='1lt7' size='340' side='right'caption='[[1lt7]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
-
===Oxidized Homo sapiens betaine-homocysteine S-methyltransferase in complex with four Sm(III) ions===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[1lt7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LT7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LT7 FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_12220488}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=SM:SAMARIUM+(III)+ION'>SM</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lt7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lt7 OCA], [https://pdbe.org/1lt7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lt7 RCSB], [https://www.ebi.ac.uk/pdbsum/1lt7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lt7 ProSAT]</span></td></tr>
-
[[1lt7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LT7 OCA].
+
</table>
-
 
+
== Function ==
-
==Reference==
+
[https://www.uniprot.org/uniprot/BHMT1_HUMAN BHMT1_HUMAN] Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline.
-
<ref group="xtra">PMID:012220488</ref><references group="xtra"/>
+
== Evolutionary Conservation ==
-
[[Category: Betaine--homocysteine S-methyltransferase]]
+
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lt/1lt7_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lt7 ConSurf].
 +
<div style="clear:both"></div>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Castro, C.]]
+
[[Category: Large Structures]]
-
[[Category: Evans, J C.]]
+
[[Category: Castro C]]
-
[[Category: Garrow, T A.]]
+
[[Category: Evans JC]]
-
[[Category: Huddler, D P.]]
+
[[Category: Garrow TA]]
-
[[Category: Jiracek, J.]]
+
[[Category: Huddler DP]]
-
[[Category: Ludwig, M L.]]
+
[[Category: Jiracek J]]
-
[[Category: Millian, N S.]]
+
[[Category: Ludwig ML]]
-
[[Category: Homocysteine metabolism]]
+
[[Category: Millian NS]]
-
[[Category: Homocysteinemia]]
+
-
[[Category: Thiol alkyl transfer]]
+
-
[[Category: Transferase]]
+

Current revision

Oxidized Homo sapiens betaine-homocysteine S-methyltransferase in complex with four Sm(III) ions

PDB ID 1lt7

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1lt7"
Personal tools