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1lw4

From Proteopedia

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{{Seed}}
 
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[[Image:1lw4.png|left|200px]]
 
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==X-ray structure of L-Threonine Aldolase (low-specificity) in complex with L-allo-threonine==
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The line below this paragraph, containing "STRUCTURE_1lw4", creates the "Structure Box" on the page.
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<StructureSection load='1lw4' size='340' side='right'caption='[[1lw4]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1lw4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LW4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LW4 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=TLP:3-HYDROXY-2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-BUTYRIC+ACID'>TLP</scene></td></tr>
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{{STRUCTURE_1lw4| PDB=1lw4 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lw4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lw4 OCA], [https://pdbe.org/1lw4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lw4 RCSB], [https://www.ebi.ac.uk/pdbsum/1lw4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lw4 ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1lw4 TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q9X266_THEMA Q9X266_THEMA]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lw/1lw4_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lw4 ConSurf].
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<div style="clear:both"></div>
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===X-ray structure of L-Threonine Aldolase (low-specificity) in complex with L-allo-threonine===
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==See Also==
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*[[Aldolase 3D structures|Aldolase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12269813}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 12269813 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12269813}}
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==About this Structure==
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1LW4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LW4 OCA].
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==Reference==
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X-ray structures of threonine aldolase complexes: structural basis of substrate recognition., Kielkopf CL, Burley SK, Biochemistry. 2002 Oct 1;41(39):11711-20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12269813 12269813]
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[[Category: Single protein]]
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[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
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[[Category: Threonine aldolase]]
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[[Category: Burley SK]]
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[[Category: Burley, S K.]]
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[[Category: Kielkopf CL]]
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[[Category: Kielkopf, C L.]]
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[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
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[[Category: Enzyme]]
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[[Category: New york structural genomix research consortium]]
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[[Category: Nysgxrc]]
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[[Category: Plp]]
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[[Category: Product complex]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Pyridoxal-5-phosphate]]
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[[Category: Structural genomic]]
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[[Category: Threonine]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 22:36:22 2008''
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Current revision

X-ray structure of L-Threonine Aldolase (low-specificity) in complex with L-allo-threonine

PDB ID 1lw4

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