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1m57

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{{Seed}}
 
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[[Image:1m57.png|left|200px]]
 
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==Structure of cytochrome c oxidase from Rhodobacter sphaeroides (EQ(I-286) mutant))==
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The line below this paragraph, containing "STRUCTURE_1m57", creates the "Structure Box" on the page.
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<StructureSection load='1m57' size='340' side='right'caption='[[1m57]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1m57]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Cereibacter_sphaeroides Cereibacter sphaeroides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M57 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M57 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3PE:1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE'>3PE</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=HEA:HEME-A'>HEA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_1m57| PDB=1m57 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m57 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m57 OCA], [https://pdbe.org/1m57 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m57 RCSB], [https://www.ebi.ac.uk/pdbsum/1m57 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m57 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/COX1_CERSP COX1_CERSP] Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme a of subunit 1 to the bimetallic center formed by heme a3 and copper B. This cytochrome c oxidase shows proton pump activity across the membrane in addition to the electron transfer.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m5/1m57_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m57 ConSurf].
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<div style="clear:both"></div>
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===Structure of cytochrome c oxidase from Rhodobacter sphaeroides (EQ(I-286) mutant))===
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==See Also==
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*[[Cytochrome c oxidase 3D structures|Cytochrome c oxidase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12144789}}, adds the Publication Abstract to the page
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[[Category: Cereibacter sphaeroides]]
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(as it appears on PubMed at http://www.pubmed.gov), where 12144789 is the PubMed ID number.
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[[Category: Large Structures]]
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[[Category: Abramson J]]
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{{ABSTRACT_PUBMED_12144789}}
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[[Category: Brezezinski P]]
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[[Category: Iwata S]]
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==About this Structure==
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[[Category: Larsson G]]
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1M57 is a 8 chains structure of sequences from [http://en.wikipedia.org/wiki/Rhodobacter_sphaeroides Rhodobacter sphaeroides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M57 OCA].
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[[Category: Svensson-Ek M]]
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[[Category: Tornroth S]]
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==Reference==
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<ref group="xtra">PMID:12144789</ref><references group="xtra"/>
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[[Category: Cytochrome-c oxidase]]
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[[Category: Rhodobacter sphaeroides]]
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[[Category: Abramson, J.]]
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[[Category: Brezezinski, P.]]
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[[Category: Iwata, S.]]
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[[Category: Larsson, G.]]
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[[Category: Svensson-Ek, M.]]
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[[Category: Tornroth, S.]]
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[[Category: Membrane protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 16:13:54 2009''
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Current revision

Structure of cytochrome c oxidase from Rhodobacter sphaeroides (EQ(I-286) mutant))

PDB ID 1m57

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